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Cancer Stem Cells: New Horizons in Cancer Therapies

  • Explores the therapeutic potential of cancer stem cells in diagnosis, prognosis, and treatment of cancer
  • Examines the current approach for identifying, isolating, and characterizing cancer stem cells
  • Evaluates the current therapeutic strategies to target cancer stem cells
  • Assesses the mechanism of radio-resistance, chemo-resistance, and drug resistance in cancer stem cells

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-vii
  2. Introduction to Cancer Stem Cells

    • Anisur Rahman Khuda-Bukhsh, Asmita Samadder, Santu Kumar Saha
    Pages 1-13
  3. Types of Cancer Stem Cells

    • Gautham Chengizkhan, Bharti Bisht, Sridhar Muthusami, Muralidharan Anbalagan, Ilangovan Ramachandran, R. Ileng Kumaran
    Pages 15-50
  4. Isolation and Characterization of Cancer Stem Cells (CSCs)

    • Namasivayam Nalini, Bichandarkoil Jayaram Pratima
    Pages 51-67
  5. Lung and Prostate Cancer Stem Cells

    • Sudeep Bose, Valentina Sain, Sartaj Khurana, Rajat Gupta
    Pages 69-85
  6. A Differential Role of miRNAs in Regulation of Breast Cancer Stem Cells

    • Shreetama Bandyopadhayaya, Chandi C. Mandal
    Pages 87-109
  7. Skin Stem Cells in Cancer

    • Monica Piccione, Rosa Di Liddo
    Pages 111-124
  8. Ocular Cancer Stem Cells: Advances in Therapeutic Interventions

    • Upasna Upadhyay, Raaghav Sen, Swathi Kaliki, Jaganmohan R. Jangamreddy
    Pages 125-136
  9. Cancer Stem Cells and Tumour Aggressiveness

    • Gautham Chengizkhan, Natarajan Bhaskaran, R. Ileng Kumaran, Ilangovan Ramachandran
    Pages 137-154
  10. Therapeutic Implication of Cancer Stem Cells

    • Sudeep Bose, Sartaj Khurana, Shrey Ashley Philip
    Pages 155-166
  11. Glioblastoma Stem Cells as a Therapeutic Target

    • Devaraj Ezhilarasan, R. Ileng Kumaran, Ilangovan Ramachandran, Santosh Yadav, Muralidharan Anbalagan
    Pages 167-184
  12. Cancer Stem Cells and Therapeutic Angiogenesis

    • Sambhavi Bhagavatheeswaran, Anandan Balakrishnan
    Pages 185-196
  13. Cancer Stem Cells as a Seed for Cancer Metastasis

    • L. Lizha Mary, M. Vasantha Kumar, R. Satish
    Pages 197-221
  14. Functionality of Intron-Specific Genes and Cancer Stem Cells in the Progression of Colorectal Cancer

    • Janani Gopi, Madhumala Gopinath, Xiao-Feng Sun, Surajit Pathak, Antara Banerjee
    Pages 223-239
  15. Technological Advancement in Cancer Stem Cell Research

    • Tanu Sharma, Chandi C. Mandal
    Pages 241-256
  16. Targeting Therapies for Cancer Stem Cells

    • Manash K. Paul, Vijay R. Marati, Yuvaraj Sambandam, Lurdes Queimado, Gautam Chaudhuri, Ilangovan Ramachandran et al.
    Pages 273-312
  17. Targeting Cancer Stem Cells by Nanoenabled Drug Delivery

    • Koyeli Girigoswami, Pragya Pallavi, Agnishwar Girigoswami
    Pages 313-337
  18. Cancer Stem Cells in Patient Survival and Therapies in Cancer

    • Ying Yang, Chao Tian, Wen-Jian Meng
    Pages 339-369
  19. Correction to: Ocular Cancer Stem Cells: Advances in Therapeutic Interventions

    • Upasna Upadhyay, Raaghav Sen, Swathi Kaliki, Jaganmohan R. Jangamreddy
    Pages C1-C1

About this book

This book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer.

It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic targets for the treatment and prevention of tumor progression.

The book also discusses the various approaches for detecting, isolating, and characterizing different cancer stem cells and signaling pathways that control their replication, survival, and differentiation. Lastly, it explores the key features and mechanisms of drug resistance, chemo-resistance, and radio-resistance in cancer stem cells to improve therapeuticrationale.

Editors and Affiliations

  • Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Chennai, India

    Surajit Pathak, Antara Banerjee

About the editors

Dr. Surajit Pathak is currently working as a Professor at Chettinad Academy of Research and Education, Kelambakkam, Chennai. He has received his Ph.D. in Zoology from the University of Kalyani, West Bengal, India in 2007, and completed his post-doctoral training at the University of Linkoping, Sweden; University of Padova, Italy; and the University of Alabama, USA.

His current research focuses on cancer biology, stem cell biology, regenerative medicine, and microRNA. He has published more than 60 research articles in peer-reviewed journals with 1270 citations. He received various research grants including core research grants from SERB (DST), and DST Indo-Italy Bi-lateral research projects.

He is an editorial board member of various respected journals including, Endocrine, Metabolic & Immune Disorders - Drug Targets.

Dr. Antara Banerjee is currently working as an Associate Professor at Chettinad Academy of Research and Education, Kelambakkam, Chennai. Antara Banerjee completed her PhD in the year 2008 and pursued her post-doctoral research at the University of Padova, Italy till 2012. Later she joined as Senior Research Associate at the University of Linkoping, Sweden till 2015. She has published over 53 impact peer-reviewed articles in International and National Journals with Citation index of 660. Her core expertise is in stem cell biology and regenerative medicine and oncology. She has been awarded DST SERB, ECR award, Government of India for a period of 2018-2021 for the project on Umbilical cord Derived Mesenchymal stem cells in modulating Colon cancer.

Bibliographic Information

  • Book Title: Cancer Stem Cells: New Horizons in Cancer Therapies

  • Editors: Surajit Pathak, Antara Banerjee

  • DOI: https://doi.org/10.1007/978-981-15-5120-8

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2020

  • Hardcover ISBN: 978-981-15-5119-2Published: 18 October 2020

  • Softcover ISBN: 978-981-15-5122-2Published: 19 October 2021

  • eBook ISBN: 978-981-15-5120-8Published: 17 October 2020

  • Edition Number: 1

  • Number of Pages: VII, 369

  • Number of Illustrations: 7 b/w illustrations, 58 illustrations in colour

  • Topics: Cancer Research, Stem Cells, Oncology, Drug Resistance

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access