Oxidative Stress in Microbial Diseases

1. Front Matter

   Pages i-xx

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2. General Aspects of Oxidant Stress in Microbial Diseases

   1. Front Matter

      Pages 1-1

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   2. Role of Reactive Oxygen Species in the Correlation Between Host and Microbes

      • Suhyun Kim, Dong Gun Lee

      Pages 3-19

   3. Blood Biomarkers of Oxidative Stress in Human and Canine Leishmaniosis

      • C. P. Rubio, D. Escribano, J. Hernández, J. J. Cerón, A. Tvarijonaviciute, S. Martínez-Subiela

      Pages 21-31

   4. Reactive Oxygen and Nitrogen Species in the Oral Cavity

      • Peng Zhou, Jessica Scoffield, Hui Wu

      Pages 33-42

   5. Role of Gut Microbiota in Combating Oxidative Stress

      • Bomba Dam, Arijit Misra, Sohini Banerjee

      Pages 43-82

   6. Role of ROS in T. cruzi Intracellular Development

      • Luciana O. Andrade, Patrícia Pereira Dias

      Pages 83-95

   7. Arginase: A Prospective Regulator of Oxidative Stress During Microbial Pathogenesis

      • Surajit Bhattacharjee

      Pages 97-109

   8. Oxidative Stress as a Determinant of Antimicrobial Action, Resistance, and Treatment

      • Satabdi Banerjee, Suman K. Nandy, Sajal Chakraborti

      Pages 111-124

3. Parasitic Diseases

   1. Front Matter

      Pages 125-125

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   2. The Biological Impact of Oxidative Metabolism in Trypanosomatid Parasites: What Is the Perfect Balance Between Reactive Species Production and Antioxidant Defenses?

      • Ana Cristina Souza Bombaça, Luiza Gervazoni Ferreira de Oliveira, Elmo Eduardo Almeida-Amaral, Rubem Figueiredo Sadok Menna-Barreto

      Pages 127-173

   3. Oxidative Stress: A Boon or Bane for Trypanosomatids Diseases?

      • Dandugudumula Ramu, Shailja Singh

      Pages 175-183

   4. Redox Regulatory Circuits as Targets for Therapeutic Intervention of Bancroftian Filariasis: Biochemical, Molecular, and Pharmacological Perspectives

      • Suprabhat Mukherjee, Nikhilesh Joardar, Santi P. Sinha Babu

      Pages 185-208

   5. Oxidative Stress and Antioxidant Defense Mechanism in the Human Enteric Protozoan Parasite Entamoeba histolytica

      • Ghulam Jeelani, Tomoyoshi Nozaki

      Pages 209-227

   6. Oxidative Stress in Protozoan Parasites: A Close Surveillance of Proteases and Endogenous Protease Inhibitors in Host-Parasite Interaction

      • Dibyapriya Roy Chowdhury, Pijush Kanti Pramanik, Tapati Chakraborti

      Pages 229-244

   7. Oxidative Stress and Antioxidants in Host Defense in Leishmaniasis

      • Carlos Kusano Bucalen Ferrari

      Pages 245-256

   8. Oxidative Stress in Entamoeba histolytica

      • Somasri Dam, Pinaki Biswas, Raktim Ghosh

      Pages 257-280

   9. Oxidative Stress Regulation in Giardia lamblia

      • Dibyendu Raj, Sandipan Ganguly

      Pages 281-296

   10. Role of Reactive Oxygen Species in Infection by the Intracellular Leishmania Parasites

       • Moumita Basu, Pijush K. Das

       Pages 297-311

4. Bacterial Diseases

   1. Front Matter

      Pages 313-313

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This book discusses recent advances in our understanding of the role of oxidants in microbial pathophysiology, providing valuable insights into the complex role of reactive oxygen species (ROS) in host-microbial interactions. The various chapters take readers through the function of ROS in infections ranging from viral to bacterial, and describe how microorganisms have developed complex strategies to not only avoid contact with phagocyte-derived oxidants, but also protect themselves from injury when oxidants are encountered. Featuring the latest research in the field of microbial diseases, this timely book is a ready reference for scientists looking to develop new anti-microbial drugs.

• Host Pathogen Interaction
• Infectious Diseases
• Microbial Infection
• Oxidative Stress
• Reactive Oxygen Species
• Apoptosis

• Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, India

  Sajal Chakraborti, Tapati Chakraborti

• Amity University, Kolkata, India

  Dhrubajyoti Chattopadhyay

• National Institute of Immunology, New Delhi, India

  Chandrima Shaha

Dr. Sajal Chakraborti is Professor of Biochemistry at the Department of Biochemistry and Biophysics, University of Kalyani, West Bengal, India. His research covers the role of proteases, oxidant and Ca2+ signalling in the pathogenesis of a variety of diseases. Dr. Chakraborti received his PhD from Calcutta University (1982) and DSc from Kalyani University (2014). He did postdoctoral research at the Johns Hopkins University (Baltimore), University of Utah (Salt Lake City) and New York Medical College (New York), USA. He received a DBT-Senior overseas research award for his research at the University of Florida, Gainesville, USA. Prof. Chakraborti been engaged in teaching and research for the past 40 years and has published over 120 original papers, 25 book chapters and 15 review articles published in different international journals of repute and also edited 12 books published by Springer.


Dr. Tapati Chakraborti is Professor of Biochemistry inthe Department of Biochemistry and Biophysics, University of Kalyani, West Bengal, India. After completion of PhD at the CSIR-Indian Institute of Chemical Biology, Kolkata (1993), she did  postdoctoral research at the University of Florida, Gainesville, Florida, USA. She is currently involved in teaching and research in elucidating Leishmania pathogenesis. She has published over 100 original research papers in reputed international journals and 20 chapters in books published by leading international publishers. She also edited three books published by Springer.


Dr. Dhrubajyoti Chattopadhyay is currently the Vice Chancellor of Amity University (Kolkata). He did post doctoral research in the Department of Cell Biology at the Roche Institute of Molecular Biology, New Jersey (1985–1987), and also in the Department of Molecular Biology at the Cleveland Clinic Foundation, Ohio (1987–1988). He was also Pro-Vice Chancellor (Academic Affairs) at Calcutta University. He has published over 100 original research articles in international journals of repute, as well as several chapters in books published by leading international publishing companies.

Dr. Chandrima Shaha is the former Director of the National Institute of Immunology, New Delhi, where she is currently the Professor of Eminence. Dr. Shaha is a J.C. Bose National Fellow, and her research interests include the understanding of modalities of cell death. Her laboratory is also involved in basic research on cancer biology. Dr. Shaha has received a number of awards, including the Ranbaxy Science Foundation Award for Basic Medical Research, Om Prakash Bhasin Award in Biotechnology and the Archana Sharma Memorial Award of the National Academy of Sciences. She has published over 100 original research papers
in different internationals of repute.

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