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Phytochemistry: An in-silico and in-vitro Update

Advances in Phytochemical Research

  • Comprehensive introduction to phytochemistry
  • Includes recent trends in both in-vitro and in-vivo properties of phytochemicals
  • A special coverage of study on novel pharmacologically active natural compounds
  • Elaborate explanation on modulation of plant properties by phytochemicals

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Table of contents (32 chapters)

  1. Front Matter

    Pages i-xii
  2. Phytochemicals and in-vitro Updates

    1. Front Matter

      Pages 1-1
    2. Phytochemicals as Sources of Drugs

      • Shahira M. Ezzat, Jaison Jeevanandam, Chukwuebuka Egbuna, Shashank Kumar, Jonathan C. Ifemeje
      Pages 3-22
    3. Synthetic Analogs of Phytochemicals

      • Chukwuebuka Egbuna, Shahira M. Ezzat, Habibu Tijjani, Vijay K. Srivastav
      Pages 23-55
    4. Phytochemicals as Anticancer Drugs: Targeting the Microtubular Network of Cancer Cells

      • Rajni Khan, Aroni Chatterjee, Hiya Ghosh, Sonia Kapoor, Shashikant Ray
      Pages 57-67
    5. Reprogramming of Tumor Associated Immune Cells by Phytochemicals: In-vitro Approaches for Cancer Treatment

      • Pradip Kumar Jaiswara, Vishal Kumar Gupta, Shiv Govind Rawat, Pratishtha Sonker, Ajay Kumar
      Pages 69-82
    6. Drug Resistance in Plasmodium sp. and Novel Antimalarial Natural Products-Emerging Trends

      • Aswathy Narayanan, Kirthana M. V. Sindhe, Laxmi Shanker Rai
      Pages 95-108
    7. Immunomodulatory Potential of Phytochemicals: Recent Updates

      • Nidhi Sharma, Herschel S. Dhekne, Sabyasachi Senapati
      Pages 133-160
    8. Anticancer and Neuroprotective Activity of Chrysin: Recent Advancement

      • Pushpendra Singh, Ravi S. Singh, Prem P. Kushwaha, Shashank Kumar
      Pages 183-202
    9. Screening of Natural Antidiabetic Agents

      • Chukwuebuka Egbuna, Santwana Palai, Israel Ehizuelen Ebhohimen, Andrew G. Mtewa, Jonathan C. Ifemeje, Genevieve D. Tupas et al.
      Pages 203-235
    10. In-vitro Models to Assess Antioxidant Potential

      • Ramesh Kumar, Ashutosh Gupta, Risha Ganguly, Abhay K. Pandey
      Pages 237-250
    11. In-vitro Models in Anticancer Screening

      • Dhanya K. C., Aditya Menon, Laxmi Shanker Rai
      Pages 251-265
    12. In-vitro Techniques to Study Cell Signaling

      • Natasha Jaiswal
      Pages 267-277
    13. In-vitro Assays for Antimicrobial Assessment

      • Jaya Kurhekar, Genevieve D. Tupas, Maria Catherine B. Otero
      Pages 279-298
    14. In-vitro Assays for Determining Anti-HIV Potential of Phytochemicals

      • Pascaline Fonteh, Walter Chingwaru, Debra Meyer, Petrina Kapewangolo
      Pages 299-313
    15. Nanoencapsulation of Phytochemicals and in-vitro Applications

      • Jordy Kim Ung Ling, Yiik Siang Hii, Jaison Jeevanandam, Yen San Chan, Michael K. Danquah
      Pages 315-330
    16. Phytotherapy in Inflammatory Lung Diseases: An Emerging Therapeutic Interventional Approach

      • Ridhima Wadhwa, Shakti Dhar Shukla, Dinesh Kumar Chellappan, Gaurav Gupta, Trudi Collet, Nicole Hansbro et al.
      Pages 331-347

About this book

Phytochemistry is the branch of science that deals with the study of plant-derived chemicals or compounds, which are also known as phytochemicals or plant-derived secondary metabolites. Plants are known to produce phytochemicals that are essential for their growth and reproduction, as they protect them from insects, pathogens, and herbivores. Some of the major groups of plant-derived secondary metabolites are phenolics, flavonoids, terpenoids, alkaloids, tannin etc.

Plant-derived phytochemicals are pharmacologically active and have the potential to cure various human diseases and disorders. Natural plant products have been known for their medicinal properties for untold years, and form the basis of several medicinal systems such as Chinese, Unani, and Ayurvedic Medicine.

This book offers an essential introduction to phytochemicals and their synthetic analogues. It discusses various in silico approaches used to identify pharmacologically active phytochemicals and their biological activities, as well as in vitro and in vivo models/assays that have been utilized for the pharmacological profiling of plant-derived products to combat cancer, diabetes, cardiovascular diseases and neurological disorders.

The intended audience includes upper-level undergraduate and graduate students; researchers and scientists from the pharmaceutical/food chemistry/nutrition sciences/biochemistry, and clinical biochemistry fields; and medical students. Sharing the latest findings, the book will familiarize these readers with the concepts, chemistry, and tremendous potential of phytochemistry.


Editors and Affiliations

  • Department of Biochemistry and Microbial Sciences, Central University of Punjab, Bathinda, India

    Shashank Kumar

  • Department of Biochemistry, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra, Nigeria

    Chukwuebuka Egbuna

About the editors

Dr. Shashank Kumar is currently working as an Assistant Professor at the Department of Biochemistry and Microbial Sciences, School of Basic and Applied Sciences, Central University of Punjab, India. 

His Professional Honors, Awards and Scholarships

  1. Life member of the Italo-Latin American Society of Ethnomedicine
  2. Life member of the Indian Sciences Congress Association, India
  3. Life Member of the Indian Academy of Biomedical Sciences Society, India
  4. Member of Publication Integrity & Ethics, London
  5. Member of the Asian Council of Science Editors, Dubai, UAE
  6. Poster Award, 27th Annual National Conference & International CME (November 25th-27th 2014)
  7. AU-CRET University Scholarship (2009-2010)
  8. UGC-Junior Research Fellowship (2009-2011)
  9. UGC-Senior Research Fellowship (2011-2014)
  10. ICMR-Senior Research Fellowship (2014)
  11. ICMR-Research Associate Fellowship (2014-2015)

 


Bibliographic Information

  • Book Title: Phytochemistry: An in-silico and in-vitro Update

  • Book Subtitle: Advances in Phytochemical Research

  • Editors: Shashank Kumar, Chukwuebuka Egbuna

  • DOI: https://doi.org/10.1007/978-981-13-6920-9

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2019

  • Hardcover ISBN: 978-981-13-6919-3Published: 09 July 2019

  • Softcover ISBN: 978-981-13-6922-3Published: 15 August 2020

  • eBook ISBN: 978-981-13-6920-9Published: 25 June 2019

  • Edition Number: 1

  • Number of Pages: XII, 577

  • Number of Illustrations: 43 b/w illustrations, 84 illustrations in colour

  • Topics: Plant Biochemistry, Plant Physiology, Receptors, Plant Anatomy/Development

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access