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Alcoholic/Non-Alcoholic Digestive Diseases

  • Book
  • © 2019

Overview

Editors:
  1. Hitoshi Yoshiji

    1. Third Department of Internal Medicine, Nara Medical University, Kashihara, Japan

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  2. Kosuke Kaji

    1. Third Department of Internal Medicine, Nara Medical University, Kashihara, Japan

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Describes the molecular mechanisms of and therapeutic strategies for alcohol- and non-alcohol-related digestive diseases

  • Presents the roles of microbiota, oxidative stress and apoptosis in connection with these diseases?

  • Showcases new pathological and therapeutic perspectives in gastric and pancreatic cancers

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-viii
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  2. Alcoholic/Non-Alcoholic Gastrointestinal Diseases

    1. Front Matter

      Pages 1-1
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    2. Alcohol-Induced DNA Injury in Esophageal Squamous Cell Carcinoma

      • Masashi Tamaoki, Yusuke Amanuma, Shinya Ohashi, Manabu Muto
      Pages 3-12

    3. Gastroesophageal Reflux Diseases and Lifestyle Factors

      • Yasuhiro Fujiwara, Risa Uemura
      Pages 13-21

    4. Post Helicobacter pylori Gastric Diseases

      • Kazunari Tominaga, Kazuhide Higuchi
      Pages 23-32

    5. New Perspectives in Gastric Cancer: Helicobacter pylori-Uninfected Pure Signet Ring Cell Carcinoma

      • Takeshi Setoyama, Shin’ichi Miyamoto, Mitsuhiro Nikaido, Hiroshi Seno
      Pages 33-41

    6. Role of Alcohol and Metabolic Diseases in Colorectal Carcinogenesis

      • Tetsuji Takayama, Yasushi Sato, Naoki Muguruma
      Pages 43-52

  3. Alcoholic/Non-Alcoholic Liver Diseases

    1. Front Matter

      Pages 53-53
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    2. Extracellular Vesicles in Alcoholic Liver Injury

      • Akiko Eguchi, Yoshiyuki Takei
      Pages 55-63

    3. Diabetes in Liver Disease

      • Takumi Kawaguchi, Dan Nakano, Takuji Torimura
      Pages 65-86

    4. Obesity and Hepatocarcinogenesis

      • Yoshio Sumida, Yuya Seko, Tasuku Hara, Akihiko Ohashi, Yukiomi Nakade, Kiyoaki Ito et al.
      Pages 87-102

    5. Microbiota in Non-alcoholic Liver Disease

      • Yuji Ogawa, Yasushi Honda, Takaomi Kessoku, Wataru Tomeno, Kento Imajo, Masato Yoneda et al.
      Pages 103-111

    6. Role of Oxidative Stress in Alcoholic/Non-Alcoholic Liver Diseases

      • Keisuke Hino
      Pages 113-125

    7. Role of Apoptosis in Liver Diseases

      • Hayato Hikita, Tetsuo Takehara
      Pages 127-135

  4. Alcoholic/Non-Alcoholic Pancreatic Diseases

    1. Front Matter

      Pages 137-137
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    2. Genetics of Pancreatitis

      • Atsushi Masamune, Tooru Shimosegawa
      Pages 139-149

    3. New Perspective in Pancreatic Cancer

      • Kota Nakamura, Takahiro Akahori, Minako Nagai, Satoshi Nishiwada, Kenji Nakagawa, Naoya Ikeda et al.
      Pages 151-161

  5. Back Matter

    Pages 163-166
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Keywords

About this book

This book describes the latest advances concerning the molecular mechanisms of and therapeutic strategies for alcohol- and non-alcohol-related digestive diseases. Alcohol abuse causes not only liver injury but can harm various organs, resulting in esophageal and colorectal cancers, GERD, pancreatitis, etc. Similar to alcoholic abuse, metabolic syndrome based on obesity and diabetes is also strongly associated with the development of various digestive diseases. Although these diseases may be differentiated by the presence or absence of alcohol intake, the pathologic findings and pathogenesis reveal a number of similarities. This volume covers clinical and basic approaches for esophageal, gastric, hepatic, colorectal and pancreatic diseases associated with alcohol abuse and metabolic syndrome; further, it discusses the roles of microbiota, oxidative stress, and apoptosis, the critical factors causing alcoholic and metabolic digestive diseases. Also, it showcases new pathological and therapeutic perspectives in gastric and pancreatic cancers.

Alcoholic/Non-Alcoholic Digestive Diseases will provide invaluable information for doctors specializing in gastroenterology and hepatology and researchers seeking new research on digestive diseases based on alcohol consumption and obesity. ​

Editors and Affiliations

  • Third Department of Internal Medicine, Nara Medical University, Kashihara, Japan

    Hitoshi Yoshiji, Kosuke Kaji

About the editors

Hitoshi Yoshiji, Third Department of Internal Medicine, Nara Medical University, Kashihara, Japan


Kosuke Kaji, Third Department of Internal Medicine, Nara Medical University, Kashihara, Japan

Bibliographic Information

  • Book Title: Alcoholic/Non-Alcoholic Digestive Diseases

  • Editors: Hitoshi Yoshiji, Kosuke Kaji

  • DOI: https://doi.org/10.1007/978-981-13-1465-0

  • Publisher: Springer Singapore

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2019

  • Hardcover ISBN: 978-981-13-1464-3Published: 25 June 2019

  • eBook ISBN: 978-981-13-1465-0Published: 11 June 2019

  • Edition Number: 1

  • Number of Pages: VIII, 166

  • Number of Illustrations: 6 b/w illustrations, 19 illustrations in colour

  • Topics: Gastroenterology, Hepatology, Metabolic Diseases

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