Overview
The first book to review the glucose-sensing receptor in pancreatic beta-cells
Helps readers understand the pathophysiology of diabetes
Reviews the complex history of the glucose-sensing machinery in pancreatic beta-cells
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Table of contents (5 chapters)
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Front Matter
Keywords
About this book
Since the 1970s, there has been much discussion about the “glucoreceptor” and “substrate site” and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the “glucoreceptor theory.”
This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells.
The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: “glucoreceptor theory”.
Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.
Editors and Affiliations
About the editor
Itaru Kojima, M.D. Professor Emeritus
Institute for Molecular & Cellular Regulation, Gunma University
Bibliographic Information
Book Title: Glucose-sensing Receptor in Pancreatic Beta-cells
Editors: Itaru Kojima
DOI: https://doi.org/10.1007/978-981-13-0002-8
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2018
Hardcover ISBN: 978-981-13-0001-1Published: 19 December 2019
eBook ISBN: 978-981-13-0002-8Published: 31 May 2018
Edition Number: 1
Number of Pages: V, 71
Number of Illustrations: 8 b/w illustrations, 7 illustrations in colour
Topics: Human Physiology, Endocrinology