Management of Advanced Prostate Cancer

1. Front Matter

   Pages i-ix

   PDF

2. Surgery for Advanced Prostate Cancer

   1. Front Matter

      Pages 1-1

      PDF

   2. Natural History of High-Risk Prostate Cancer

      • Sangjun Yoo, In Gab Jeong

      Pages 3-9

   3. Identifying the Best Candidate for Radical Prostatectomy in High-Risk Prostate Cancer

      • Jung Jun Kim, Sung Kyu Hong

      Pages 11-19

   4. Neoadjuvant Therapy Prior to Radical Prostatectomy

      • Se Young Choi, Choung Soo Kim

      Pages 21-33

   5. Robot-Assisted Radical Prostatectomy for High-Risk Prostate Cancer

      • Taekmin Kwon, Jun Hyuk Hong

      Pages 35-39

   6. Pelvic Lymphadenectomy for High-Risk Prostate Cancer

      • Chunwoo Lee, Dalsan You

      Pages 41-49

   7. Adjuvant Therapy in Locally Advanced Prostate Cancer

      • Jae Heon Kim

      Pages 51-57

   8. Role of Radical Prostatectomy in the Management of Metastatic Prostate Cancer

      • Hyeong Dong Yuk, Cheol Kwak

      Pages 59-63

3. Radiotherapy for Advanced Prostate Cancer

   1. Front Matter

      Pages 65-65

      PDF

   2. The Roles of Radiotherapy, Androgen Deprivation Therapy, and Their Combination for Locally Advanced Prostate Cancer

      • Sung Uk Lee, Kwan Ho Cho

      Pages 67-76

   3. External Beam Radiotherapy for Advanced Prostate Cancer: Dose, Technique, and Fractionation

      • Yeon Joo Kim, Young Seok Kim

      Pages 77-83

   4. Radiotherapy for Prostate Cancer Patients with Pelvic Lymph Node Metastasis

      • Seung Gyu Park, Won Park

      Pages 85-93

   5. Emerging Role of Radiotherapy in Stage IV Prostate Cancer

      • Changhoon Song, Jae-Sung Kim

      Pages 95-103

   6. Adjuvant and Salvage Radiation Therapy for Prostate Cancer After Radical Prostatectomy

      • Joo Hwan Lee, Sung Hwan Kim

      Pages 105-113

4. Androgen Deprivation Therapy for Advanced Prostate Cancer

   1. Front Matter

      Pages 115-115

      PDF

   2. Immediate vs. Delayed ADT for Recurrent Prostate Cancer

      • Tae Heon Kim, Seong Il Seo

      Pages 117-120

   3. Intermittent Versus Continuous ADT for Advanced Prostate Cancer

      • Kyu Won Lee, Ji Youl Lee

      Pages 121-125

   4. LHRH Agonist and Antagonist for Prostate Cancer

      • Jin Bong Choi, Jun Sung Koh

      Pages 127-132

   5. Abiraterone or Enzalutamide in Chemotherapy-Naïve Metastatic CRPC

      • Ho Seok Chung, Taek Won Kang

      Pages 133-137

This textbook summarizes the state of the art in the management of locally advanced and metastatic prostate cancer with the aim of providing the knowledge required for optimal treatment decision making in individual cases. Readers will find comprehensive coverage of the latest developments in surgery, radiotherapy, androgen deprivation therapy (ADT), chemotherapy, and immunotherapy. The role of the hormonal therapies abiraterone and enzalutamide and docetaxel-based chemotherapy in castration-resistant prostate cancer and hormone-sensitive metastatic disease is carefully evaluated. Among the other therapies discussed are LHRH agonists and antagonists, cabazitaxel, radium-223, and various novel agents still under clinical trials. The section on surgical approaches addresses, among other topics, the use of robot-assisted radical prostatectomy, pelvic lymphadenectomy, and the benefits of adjuvant and neoadjuvant therapy. The current role of external beam radiotherapy, alone or in combination with ADT and brachytherapy, for locally advanced disease is reviewed. Management of Advanced Prostate Cancer will be a valuable resource for practitioners at all levels of expertise.

• Prostate Cancer
• radiotherapy
• chemotherapy
• immunotherapy
• cancer management
• metastatic prostate cancer
• surgical oncology

• Department of Urology, Asan Medical Center, Seoul, Korea (Republic of)

  Choung Soo Kim

Choung Soo Kim, M.D., Professor, Department of Urology, Asan Medical Center, Asan Medical Center Ulsan University, Seoul, Republic of Korea.

Policies and ethics