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  • © 2017

Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation

Authors:

  • Providing a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle

  • Focusing on the cutting-edge developments in vasoactive agents, enzymes, and transduction mechanisms

  • Covering recent advances in the regulation of cerebral, coronary, and pulmonary circulation

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-xiii
  2. General Properties of Vasculature

    1. Front Matter

      Pages 1-1
    2. Architecture of the Blood Vessels

      • Yuansheng Gao
      Pages 3-12
    3. Ultrastructure of Vascular Smooth Muscle

      • Yuansheng Gao
      Pages 13-25
    4. Vascular Endothelium

      • Yuansheng Gao
      Pages 27-40
    5. Metabolism of Vascular Smooth Muscle

      • Yuansheng Gao
      Pages 69-80
  3. Regulators of Vasoreactivity

    1. Front Matter

      Pages 81-81
    2. Neurotransmitters

      • Yuansheng Gao
      Pages 83-96
    3. Endothelium-Derived Factors

      • Yuansheng Gao
      Pages 97-111
    4. Local Metabolic Factors and Vasoactivity

      • Yuansheng Gao
      Pages 113-126
  4. Intracellular Signalings

    1. Front Matter

      Pages 137-137
    2. Intracellular Ca2+ Regulation

      • Yuansheng Gao
      Pages 139-154
    3. Cyclic AMP Signaling

      • Yuansheng Gao
      Pages 169-180
    4. Cyclic GMP Signaling

      • Yuansheng Gao
      Pages 181-195
  5. Heterogeneity in Vasoreactivity

    1. Front Matter

      Pages 197-197
    2. Coronary Vasoreactivity

      • Yuansheng Gao
      Pages 199-214

About this book

This book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on recently identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the regulation of cerebral, coronary and pulmonary circulation as well as vascular activity under hypoxia and ageing. The contraction and dilatation activities of vasculature are of fundamental importance for maintaining circulation homeostasis and adapting physiological changes. Over the last four decades, there have been significant advances in our understanding of the biochemical, structural, genetic, physiological, and pharmacological aspects of vascular activity regulation, and these insights into the responsiveness of blood vessels under normal and pathophysiological conditions help to provide valuable weapons in the fight vascular diseases. The book is of interest to researchers and graduate students, both in basic research and in clinic settings, in the field of vascular biology.

Authors and Affiliations

  • Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing, China

    Yuansheng Gao

About the author

Dr. Yuansheng Gao is a professor at the Department of Physiology and Pathophysiology at Peking University Health Science Center, and an honorary professor at the Department of Pharmacology and Pharmacy at the University of Hong Kong’s Li Ka Shing Faculty of Medicine. He has been a member of the Asian Society for Vascular Biology council since 2005 and the review editor for the journal “Frontiers in Vascular Physiology” since 2011. He has been involved in research on the signaling transduction in vascular smooth muscle cells for more than 20 years, and has published over 90 original research and review articles in this field.

Bibliographic Information

  • Book Title: Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation

  • Authors: Yuansheng Gao

  • DOI: https://doi.org/10.1007/978-981-10-4810-4

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2017

  • Softcover ISBN: 978-981-13-5237-9Published: 12 December 2018

  • eBook ISBN: 978-981-10-4810-4Published: 14 June 2017

  • Edition Number: 1

  • Number of Pages: XIII, 286

  • Number of Illustrations: 10 b/w illustrations, 33 illustrations in colour

  • Topics: Human Physiology, Cell Physiology, Angiology, Molecular Medicine

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access