Recent Advances in Redox Active Plant and Microbial Products

1. Front Matter

   Pages i-xiv

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2. Introduction

   • Claus Jacob, Torsten Burkholz, Gilbert Kirsch, Alan Slusarenko, Paul G. Winyard

   Pages 1-11

3. Connecting Section Between Chapters 1 and 2

   1. Front Matter

      Pages 13-13

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   2. Antioxidants: A Premature Scientific Hypothesis that Reshuffled the Traditional Food Pyramid

      • Agnieszka Bartoszek

      Pages 15-28

4. Connecting Section Between Chapters 2 and 3

   1. Front Matter

      Pages 29-30

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   2. The Modern Art of Identification of Natural Substances in Whole Plants

      • Patrick Chaimbault

      Pages 31-94

5. Connecting Section Between Chapters 3 and 4

   1. Front Matter

      Pages 95-96

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   2. A Word on Redox

      • Torsten Burkholz, Claus Jacob

      Pages 97-116

6. Connecting Section Between Chapters 4 and 5

   1. Front Matter

      Pages 117-117

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   2. Oxidative Stress, Antioxidants, and Chemoprevention: On the Role of Oxidant-Induced Signaling in Cellular Adaptation

      • Lars-Oliver Klotz

      Pages 119-146

7. Connecting Section Between Chapters 5 and 6

   1. Front Matter

      Pages 147-147

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   2. The French Paradox at Tea Time: From Antioxidant Flavonoids and Stilbenes Toward Bio-inspired Synthetic Derivatives

      • Oualid Talhi, Diana C. G. A. Pinto, Artur M. S. Silva

      Pages 149-189

8. Connecting Section Between Chapters 6 and 7

   1. Front Matter

      Pages 191-191

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   2. Bioreactivity of Resveratrol Toward Inflammation Processes

      • Norbert Latruffe, Allan Lançon, Emeric Limagne, Jean-Jacques Michaille

      Pages 193-207

9. Connecting Section Between Chapters 7 and 8

   1. Front Matter

      Pages 209-210

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   2. Flavanols and Proanthocyanidins

      • Hadi Ebrahimnejad, Torsten Burkholz, Claus Jacob

      Pages 211-232

10. Connecting Section Between Chapters 8 and 9

    1. Front Matter

       Pages 233-234

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    2. The Cellular ‘Thiolstat’ as an Emerging Potential Target of Some Plant Secondary Metabolites

       • Martin C. Gruhlke, Alan J. Slusarenko

       Pages 235-262

11. Connecting Section Between Chapters 9 and 10

    1. Front Matter

       Pages 263-263

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    2. Thiosulfinates, Organic Polysulfanes, and Related Compounds: From an Unusual Chemistry Toward a Wealth of Potential Applications

       • Ifeanyi D. Nwachukwu, Alan J. Slusarenko

       Pages 265-288

Nature endows us with a treasure chest of Green Gold full of amazing ‘redox-active’ substances which interfere with numerous biological processes in our own body, in animals, bacteria, fungi and plants. Whilst such natural products are all around and also in us, we still do not fully understand how these compounds actually work. This book attempts to resolve some of the mysteries and riddles associated with such products. Written by more than thirty international experts from academia and industry, it places a focus on modern developments in this field and considers such natural products from various angles, from their isolation and characterization all along to product development and commercialization. Throughout, the reader will be confronted with modern approaches which enable the efficient identification and isolation of new natural products, help to elucidate their mode(s) of action and permit practical uses in Medicine, Cosmetics, Agriculture, Industry and as functional foods.

• Green Phytoprotectants
• Intracellular Thiolstat
• Polyphenols
• Reactive Sulfur Species
• Redox Modulation

• Bioorganic Chemistry/School of Pharmacy, University of Saarland, Saarbrücken, Germany

  Claus Jacob, Torsten Burkholz

• SRSMC UMR 7565, Université de Lorraine, Metz, France

  Gilbert Kirsch

• Plant Physiology (Bio III), RWTH Aachen University, Aachen, Germany

  Alan Slusarenko

• Medical School, University of Exeter, Exeter, United Kingdom

  Paul G. Winyard

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