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  • Book
  • © 2015

Allergy Bioinformatics

Editors:

  • Introduces the bioinformatics resources and tools available for the study of allergenicity
  • Presents mechanism of allergies
  • Covers allergen database
  • Includes supplementary material: sn.pub/extras

Part of the book series: Translational Bioinformatics (TRBIO, volume 8)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xii
  2. Introduction

    • Shan Wang, Ailin Tao, Eyal Raz
    Pages 1-13
  3. Allergic Disease Epidemiology

    • Juan Wang, Junshu Wu, He Lai
    Pages 15-41
  4. The Pathogenesis of Allergy: A Brief Introduction

    • Zhi-Qiang Liu, Ping-Chang Yang
    Pages 43-48
  5. Genetics and Epigenetic Regulation in Allergic Diseases

    • Chang-Hung Kuo, Chih-Hsing Hung
    Pages 49-65
  6. Cross-Reactivity

    • Wen Li, Zehong Zou
    Pages 67-92
  7. Allergen Gene Cloning

    • Xue-Ting Liu, Ailin Tao
    Pages 105-119
  8. High Throughput Screening of Allergy

    • Junyan Zhang, Ailin Tao
    Pages 121-137
  9. Antigenicity, Immunogenicity, Allergenicity

    • Jianguo Zhang, Ailin Tao
    Pages 175-186
  10. Strategies for the Modification and Evaluation of Allergenicity

    • Zhaoyu Liu, Huifang Chen, Ailin Tao
    Pages 195-221
  11. Bioinformatics Methods to Predict Allergen Epitopes

    • Ying He, Ailin Tao
    Pages 223-238
  12. Allergen Database

    • Yuyi Huang, Ailin Tao
    Pages 239-251

About this book

The book introduces the bioinformatics resources and tools available for the study of allergenicity. Allergy symptoms affect more than 25% of the population in industrialized countries. At the same time, biotechnology is a rapidly developing field, which often involves the introduction of potentially allergenic novel proteins into drugs or foods. It is essential to avoid transferring a gene that encodes a major allergenic protein (from any source) into a drug/food crop that did not previously contain that protein. Accurately distinguishing candidate genes from allergens before transferring them into a drug or food would aid preventive efforts to curb the rising incidence of allergies. Several public databases have been created in response to increasing allergen data. The resources provided by these databases have paved the way for the creation of specialized bioinformatics tools that allow allergenicity to be predicted. The book is a useful resource for biologists and biomedical informatics scientists, as well as clinicians. Dr. Ailin Tao is the chief of Guangdong Province Key Laboratory of Allergy & Clinical Immunology, Principal Investigator of the State Key Laboratory of Respiratory Disease, the Second Affiliated Hospital of Guangzhou Medical University; Dr. Prof. Eyal Raz is a Professor of Medicine at University of California, San Diego, La Jolla, California, USA. They collaborate very well on allergy research and this book editi

ng.

Reviews

“A comprehensive overview of the molecular basis of allergic diseases, its molecular basis, and how bioinformatics tools can help improve our understanding. This first edition will guide immunologists and professionals dedicated to allergic diseases as they enter this field. This book facilitates a thorough understanding of how bioinformatics tools impact advances in allergic diseases research. It presents an overview of basic aspects and to understand the use of several computational tools.” (Marlon Múnera, World Allergy Organization, WAO Medical Book Reviews, worldallergy.org, September, 2016)

Editors and Affiliations

  • The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China

    Ailin Tao

  • Department of Medicine, University of CA, San Diego, La Jolla, USA

    Eyal Raz

Bibliographic Information

  • Book Title: Allergy Bioinformatics

  • Editors: Ailin Tao, Eyal Raz

  • Series Title: Translational Bioinformatics

  • DOI: https://doi.org/10.1007/978-94-017-7444-4

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2015

  • Hardcover ISBN: 978-94-017-7442-0Published: 13 November 2015

  • Softcover ISBN: 978-94-024-0403-6Published: 23 August 2016

  • eBook ISBN: 978-94-017-7444-4Published: 05 November 2015

  • Series ISSN: 2213-2775

  • Series E-ISSN: 2213-2783

  • Edition Number: 1

  • Number of Pages: XII, 251

  • Number of Illustrations: 6 b/w illustrations, 39 illustrations in colour

  • Topics: Molecular Medicine, Bioinformatics

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access