Practical Applications of Prostaglandins and their Synthesis Inhibitors

1. Front Matter

   Pages i-x

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2. General Introduction and Practical Implications of some Pharmacological Actions of Prostaglandins, Thromboxanes and their Synthesis Inhibitors

   • K. Hillier, S. M. M. Karim

   Pages 1-24

3. Prostaglandins and Nasal Patency

   • P. G. Adaikan, S. M. M. Karim, N. Kunaratnam

   Pages 25-38

4. PGE1 in lschaemic Peripheral Vascular Disease

   • L. A. Carlson, A. G. Olsson

   Pages 39-51

5. Prostaglandins, their Synthesis Inhibitors and Ductus Arteriosus

   • F. Coceani, P. M. Olley

   Pages 53-75

6. Prostaglandins and Angiography

   • D. Legge

   Pages 77-87

7. Prostaglandins in Gastro-intestinal Disease

   • A. Robert

   Pages 89-102

8. Prostaglandins and their Synthesis Inhibitors in Bartter’s Syndrome

   • M. Fichman

   Pages 103-137

9. Prostaglandins and their Synthesis Inhibitors in Migraine

   • J. Vardi, J. M. Rabey, M. Streifler

   Pages 139-148

10. Prostaglandins and Cancer

    • A. Bennett

    Pages 149-188

11. Veterinary Uses of Prostaglandins

    • M. J. Cooper, D. Hammond, R. H. Schultz

    Pages 189-216

12. Prostaglandins and their Synthesis Inhibitors in Primary Dysmenorrhoea

    • N. Wiqvist

    Pages 217-235

13. Prostaglandins and their Synthesis Inhibitors in Dysfunctional Uterine Bleeding

    • M. Toppozada

    Pages 237-265

14. Menstrual Regulation with Prostaglandins

    • M. Bygdeman

    Pages 267-282

15. Preoperative Cervical Dilatation with Prostaglandins

    • S. M. M. Karim, R. N. V. Prasad

    Pages 283-299

16. Prostaglandins for Pre-induction Cervical Ripening

    • A. A. Calder

    Pages 301-318

17. Termination of Abnormal Intrauterine Pregnancy with Prostaglandins

    • S. M. M. Karim, S. C. Ng, S. S. Ratnam

    Pages 319-374

18. Termination of Second Trimester Pregnancy with Prostaglandins

    • S. M. M. Karim

    Pages 375-409

19. Prostaglandins and their Inhibitors in Premature Labour

    • H. Zuckerman, S. Harpaz-Kerpel

    Pages 411-435

20. Induction of Labour with Prostaglandins

    • J.-J. Amy, M. Thiery

    Pages 437-446

This is the fourth in a series of books on Advances in Prostaglandin Research published by MTP Press. From laboratory and animal studies a large number of practical applications of prostaglandins have been identified. In some areas clinical trials have also been carried out. There is usually a long time interval between identifying practical applications of new drugs and clinical trials. Most of the information on practical applications of prostaglandins is scattered in different journals. Although a number of books dealing with prostaglandin research have been published (including some on practical applications in specific areas, e.g. reproduction) there is no single volume dealing with all areas of practical applications of these substances. This book aims at filling this gap and should be of interest to clinicians as well as to medical and basic scientists in academic institutions and in the pharmaceutical industry. In some areas, exciting potential applications of prostaglandins have been identified from basic research but clinical trials have so far not been carried out. Such areas of practical applications are covered in a separate intro­ ductory chapter. All contributors to the volume are scientists and clinicians actively engaged in prostaglandin research and most are recognized authorities in specific areas. The need for rapid publication in a fast-expanding field is obvious.

• Laboratory
• angiography
• cancer
• clinical trial
• drugs
• grain
• migraine
• pharmaceutical industry
• pharmacology
• pregnancy
• production
• regulation
• reproduction
• research
• vascular disease

• Department of Obstetrics and Gynaecology, University of Singapore, Kandang Kerbau Hospital, Singapore

  Sultan M. M. Karim

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