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NMR in Living Systems

  • Book
  • © 1986

Overview

Editors:
  1. Theodore Axenrod

    1. Department of Chemistry, City College of the City University of New York, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Giulio Ceccarelli

    1. Institute of Physical Chemistry, University of Pisa, Italy

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Nato Science Series C: (ASIC, volume 164)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-viii
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  2. An Overview of Biological Applications of NMR

    • Cherie L. Fisk, Edwin D. Becker
    Pages 1-17

  3. Theoretical Background to High Resolution NMR Parameters and Nuclear Shielding Calculations

    • G. A. Webb
    Pages 19-37

  4. An Introduction to NMR Relaxation Mechanisms

    • Edwin D. Becker, Cherie L. Fisk
    Pages 39-52

  5. Some Calculations of Nuclear Spin-Spin Couplings

    • G. A. Webb
    Pages 53-65

  6. Two-Dimensional NMR Spectroscopy

    • Ad Bax
    Pages 67-94

  7. NMR Data Processing in Computers

    • Dieter Ziessow
    Pages 95-107

  8. The Physical Basis of NMR Tomography

    • F. De Luca, B. C. De Simone, B. Maraviglia, R. Campanella, C. Casieri
    Pages 109-116

  9. The Sensitivity Of the NMR Imaging Experiment

    • D. I. Hoult
    Pages 117-122

  10. The Use of Models in the Interpretation of NMR Images

    • Aldo Rescigno, Charles C. Duncan
    Pages 123-156

  11. Chemical Shift Imaging

    • Derek Shaw
    Pages 157-168

  12. Medical Aspects of Magnetic Resonance

    • L. D Hall, W. A. Stewart
    Pages 169-175

  13. MR-Imaging and Spectroscopy Offering New Possibilities in Medical Diagnoses

    • A. Ganssen
    Pages 177-191

  14. Cost and Availability of Commercial NMR Equipment; and Requirements for Housing, Installation and Operation

    • L. D. Hall
    Pages 193-197

  15. Practical Aspects Of “In Vitro” and “In Vivo” T1 and T2 Measurements

    • C. A. Boicelli, A. M. Baldassarri
    Pages 199-216

  16. Construction of a Combined High Resolution NMR Spectrometer-Tomograph

    • L. D. Hall, H. Chow, S. Luck, T. Marcus, C. Neale, B. Powell et al.
    Pages 217-230

  17. Gathering Metabolic Information Using 13C and 1H High Resolution Spectra of Living Systems

    • J. R. Alger
    Pages 231-264

  18. Non-Invasive Localized Volume Spectroscopy of Animals: Prospects from the Viewpoint of the High Resolution Spectroscopist

    • J. R. Alger
    Pages 265-278

  19. NMR Methods for Measuring Cation Concentrations in Biological Systems

    • J. Feeney
    Pages 279-289

  20. NMR Spectroscopy of Intracellular Sodium Ions in Living Cells

    • Raj K. Gupta
    Pages 291-308
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Keywords

About this book

In the four decades since its discovery nuclear magnetic resonance (NMR) has become an indispensable tool for obtaining chemical information often. inaccessible by other methods. With the development of instruments of increasingly higher magnetic field strengths, the integration of powerful computers and the availability of an expanding array of flexible software new applications and developments have proliferated rapidly. Among the more exciting new advances is the use of NMR spectroscopy to probe biological systems. The last ten years have witnessed tremendous progress in the development of new NMR imaging and spectroscopic techniques for research and diagnostic applications. The ability to investigate metabolic processes and anatomical structure of intact biological systems under conditions that are totally non-destructive and non-invasive clearly provides much of the impetus for the intense activity that has been generated in the fields of medicine, radiology and the allied basic sciences. Significant advances have been made in this brief period: Whole-body proton NMR imaging today provides anatomical definition of normal and abnormal tissue with a contrast and detection sensitivity often superior to those of X-ray computed tomography and other competing imaging methods. Biochemical pathways, using NMR spectroscopy of protons, carbon-13 and phosphorus-31 nuclei in live animals and man can readily be followed by surface-coil methods to detect metabolites in localized regions. Indicative of the importance and widespread acceptance of these techniques is the explosive growth that the NMR literature is experiencing. This augers well for the future.

Editors and Affiliations

  • Department of Chemistry, City College of the City University of New York, USA

    Theodore Axenrod

  • Institute of Physical Chemistry, University of Pisa, Italy

    Giulio Ceccarelli

Bibliographic Information

  • Book Title: NMR in Living Systems

  • Editors: Theodore Axenrod, Giulio Ceccarelli

  • Series Title: Nato Science Series C:

  • DOI: https://doi.org/10.1007/978-94-009-4580-7

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: D. Reidel Publishing Company, Dordrecht, Holland 1986

  • Hardcover ISBN: 978-90-277-2174-7Due: 28 February 1986

  • Softcover ISBN: 978-94-010-8535-9Published: 13 October 2011

  • eBook ISBN: 978-94-009-4580-7Published: 06 December 2012

  • Series ISSN: 1389-2185

  • Edition Number: 1

  • Number of Pages: 418

  • Topics: Radiotherapy

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