Current Status of Clinical Cardiology 1990

1. Front Matter

   Pages i-x

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2. Experimental cardiac transplantation

   • P. M. Chisholm

   Pages 1-13

3. Cardiopulmonary resuscitation

   • D. A. Zideman

   Pages 15-27

4. Practical cardiac pacing

   • J. Perrins

   Pages 29-48

5. The pathology of immunological injury to the heart

   • E. G. J. Olsen

   Pages 49-75

6. Amyloid heart disease

   • C. M. Oakley

   Pages 77-90

7. Fetal echocardiography

   • L. D. Allan

   Pages 91-117

8. The primary hyperlipidaemias — diagnosis and management

   • D. J. Betteridge

   Pages 119-134

9. Investigation and management of unstable angina

   • P. A. Crean

   Pages 135-164

10. Pathophysiology of angina pectoris

    • A. A. Quyyumi

    Pages 165-189

11. Investigation and management of acute myocardial infarction

    • A. Cheng, C. D. J. Ilsley

    Pages 191-228

12. The use of gene probes to investigate the aetiology of arterial diseases

    • A. Tybjærg-Hansen, S. E. Humphries

    Pages 229-252

13. Back Matter

    Pages 253-258

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D.G.JULIAN Cardiology has been advancing on a broad front and in recent years we have learned much about the basic mechanisms underlying heart disease, and developed many new methods of diagnosis and treatment. This book discusses in depth some of the most important aspects of these. One of the most exciting areas of research has been in molecular biology; Tybjrerg-Hansen and Humphries describe how, following the pioneering Nobel prize-winning work of Goldstein and Brown, gene probes are being used to discover the genetic causes of coronary artery disease, especially in the hyperlipidaemias but also in thrombotic states. These developments, together with the introduction of powerful lipid-lowering agents has triggered interest in the primary hyperlipidaemias, which are frequently hereditary. Betteridge discusses their diagnosis and management. Quyyumi describes how a greater knowledge of the physiology and pathology of the coronary circulation has led to a better understanding of the causes of angina pectoris and of 'silent ischaemia'. Crean deals with the difficult topic of unstable angina, which has caused a lot of controversy in the past, but whose investigation and management is now broadly agreed.

• angina pectoris
• cardiology
• echocardiography
• heart
• heart disease
• myocardial infarction
• physiology
• transplantation

• British Heart Foundation, London, UK

  D. G. Julian

• University of Newcastle upon Tyne, UK

  D. G. Julian

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