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GnRH Analogues in Cancer and Human Reproduction

Volume IV Precocious Puberty, Contraception and Safety Issues

  • Book
  • © 1990

Overview

Editors:
  1. B. H. Vickery

    1. Syntex Research, Institute of Biological Science, Palo Alto, USA

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  2. B. Lunenfeld

    1. Institute of Endocrinology, Sheba Medical Center and Bar Ilan University, Remat Gan, Israel

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-xxviii
    Download chapter PDF

  2. Introduction

    • Brian H. Vickery, Bruno Lunenfeld
    Pages 1-3

  3. Reversible Inhibition of Sexual Maturation in Male Rats: A Safety Evaluation for the Use of LHRH Analogues in Precocious Puberty

    • J. Sandow, K. Engelbart, W. von Rechenberg, M. Hahn, S. Kille
    Pages 5-22

  4. Mechanism of Action of GnRH Analogues in Sexual Maturation and Function

    • Michel L. Aubert, Renee Kreuter, Pierre C. Sizonenko
    Pages 23-38

  5. Should All Girls with Central Precocious Puberty be Treated by LHRH Analogue?

    • R. Brauner, R. Rappaport
    Pages 39-41

  6. Long Term Experience with a Superactive GnRH Analog in the Treatment of Precocious Puberty

    • R. Kauli, A. V. Schally, Z. Laron
    Pages 43-52

  7. Effects of GnRH Analogues on Growth and Bone Maturation: A Role for Growth Factors and Adrenal Androgens

    • S. L. S. Drop, W. Oostdijk, A. J. H. Odink, C.-J. Partsch, R. Hummelink, W. G. Sippell
    Pages 53-60

  8. Growth Patterns and Skeletal Maturation During Sex Steroid Suppression and Reactivation in Central Precocious Puberty

    • Paul A. Boepple, M. Joan Mansfield, John D. Crawford, John F. Crigler Jr., Kathleen Link, Robert M. Blizzard et al.
    Pages 61-74

  9. Precocious Puberty: Pathophysiology and Treatment

    • Selna L. Kaplan, David Stephure, Jasna Knezvic, Melvin M. Grumbach
    Pages 75-83

  10. Effects of GnRH Agonists on Pituitary Gonadotropins: Dissociated Secretion of Subunits in Children with Precocious Puberty Treated with [D-Trp6]LHRH Microcapsules

    • M. Roger, N. Lahlou, J. L. Chaussain, C. Fouprie, R. Francois, J. E. Toublanc et al.
    Pages 85-98

  11. Testicular Changes in Patients with Buserelin for Precocious Puberty

    • W. J. Tze, B. Gilks, H. Kitson, R. M. Couch, G. P. Taylor, P. Merat
    Pages 99-105

  12. Influence of Buserelin on Testicular Tissue After Long-Term Treatment for Precocious Puberty and Prostatic Cancer

    • F. Hadziselimovic
    Pages 107-114

  13. GnRH Analogues in the Development of a Male Contraceptive: Importance of Testosterone Substitution and Reversibility of Pituitary and Testicular Suppression

    • Gerhard F. Weinbauer, Eberhard Nieschlag
    Pages 115-125

  14. Clinical Pharmacology of LHRH Antagonists

    • Spyros N. Pavlou, Jean Rivier, Wylie Vale, Themis Kamilaris
    Pages 127-131

  15. Clinical Studies with the Nal-Glu GnRH Antagonist

    • Ph. Bouchard, S. Hajri, N. Lahlou, M. Roger, S. Brailly, S. Dubourdieu et al.
    Pages 133-140

  16. The Clinical Relevance of Bone Mass Measurements

    • I. Fogelman, A. Rodin
    Pages 141-152

  17. Bone Calcium Dynamics in Women with Declining Estrogen Levels

    • Daniel Kenigsberg, Magdalen E. Hull
    Pages 153-160

  18. Effects of GnRH Agonist-Induced Ovarian Suppression on Calcium Homeostasis and Bone Metabolism in Premenstrual Women

    • S. Waibel, H. W. Minne, Th. Bremen, S. H. Scharla, R. Shiffl, C. Wüster et al.
    Pages 161-170

  19. GnRH Analogs and Safety

    • Florence Comite
    Pages 171-183

  20. Management of Post-Marketing Surveillance Following Short- and Long-Term Use of GnRH Analogues

    • Carlos A. Schaffenburg
    Pages 185-190
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Keywords

About this book

These four volumes comprising "GnRH Analogues in Cancer and Human Reproduction" are a distillation of the presentations of the invited speakers at a landmark International Symposium bearing the same name, organized by one of us (B. L. ) and held in Geneva, Switzerland in February 1988. The Symposium was truly interdisciplinary spanning gonadal hormone dependent disease including various forms of cancer and ranging to control of fertility, both pro- and conception. The international flavor can be caught from the 480 participants and 259 contributors drawn from 14 countries. The Symposium, and therefore this book, would not have been possible without the backing of The International Committee for Research in Reproduction and the sponsorship of the International Society of Gynecologic Endocrinology, The Swiss Society of Fertility and Sterility, The University of Geneva School of Medicine, The Swiss Society of Endocrinology and The US Foundation for Studies in Reproduction Inc. , and help from the World Health Organization. B. H. Vickery B. Lunenfeld June 1989 LIST OF CONTRIBUTORS TO THE SERIES H. Bartermann A. Abbondante First Institute of Obstetrics and Urologische Universitatsklinik Kiel Gynecology Arnold-Heller Strasse 7 University "La Sapienza" D-2300 Kiel 1, FRG Rome,ltaly M. Bartholomew P. Abel Department of Medicine/Endocrinology Department of Urology Milton S. Hershey Medical Center Hammersmith Hospital Pennsylvania State University DuCane Road PO Box 850, Hershey, PA 17033, USA London W12 OHS, UK D. Beck H.

Reviews

`(These books) can be highly recommended; it should in fact be considered a serious lack if they are not present to complete the references on GnRH analogues.'
Annals of Oncology 2 (7) 1991

Editors and Affiliations

  • Syntex Research, Institute of Biological Science, Palo Alto, USA

    B. H. Vickery

  • Institute of Endocrinology, Sheba Medical Center and Bar Ilan University, Remat Gan, Israel

    B. Lunenfeld

Bibliographic Information

  • Book Title: GnRH Analogues in Cancer and Human Reproduction

  • Book Subtitle: Volume IV Precocious Puberty, Contraception and Safety Issues

  • Editors: B. H. Vickery, B. Lunenfeld

  • DOI: https://doi.org/10.1007/978-94-009-0725-6

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 1990

  • Softcover ISBN: 978-94-010-6811-6Published: 28 October 2011

  • eBook ISBN: 978-94-009-0725-6Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXVIII, 195

  • Topics: Oncology, Diabetes, Gynecology, Pharmacology/Toxicology

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