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The Search for New Anticancer Drugs

  • Book
  • © 1992

Overview

Part of the book series: Cancer Biology and Medicine (CABM, volume 3)

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Table of contents (10 chapters)

Keywords

About this book

Most of the anti-cancer drugs in use today were discovered by happy accident rather than design, yet the rational design of better anti-cancer drugs remains a cherished goal, and one of the most important challenges facing medical science.
This book represents a compilation of views and progress reports which illustrate the diversity of approaches to the problem. Recent research has confirmed the belief that critical genetic changes are at work in cancer cells. The genome, then (DNA in biochemical terms), surely represents a critical target for specific chemotherapy of cancer, and several chapters address the issue of attacking DNA, gene targetting, and the like. Others deal with principles of rational design, exploitation of novel modalities and targets, or the nuts and bolts of antitumour drug testing. While no attempt has been made to provide a comprehensive coverage of this wide-ranging and vitally important subject, the present volume in the series will provide much food for thought.

Reviews

` Overall, then, a well-edited and pretty up-to-date collection of interesting and useful articles. I would recommend it for a post-graduate seminar or debate on the medicinal chemistry of cancer. '
Annals of Oncology

` This book is recommended both for scientists engaged in anticancer drug development and for the interested outsider. In general it is well produced and, apart from a few exceptions, most of the chemical structures are refreshingly well drawn. The individual chapters are nicely sub-sectioned and all are comprehensively referenced to the primary literature; indeed some of the references have already been useful in our own work. '
Clinical Oncology, 5:4

Editors and Affiliations

  • University of Cambridge, UK

    M. J. Waring

  • CRC Human Cancer Genetics Research Group, Department of Pathology, University of Cambridge, UK

    B. A. J. Ponder

Bibliographic Information

  • Book Title: The Search for New Anticancer Drugs

  • Editors: M. J. Waring, B. A. J. Ponder

  • Series Title: Cancer Biology and Medicine

  • DOI: https://doi.org/10.1007/978-94-009-0385-2

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 1992

  • Softcover ISBN: 978-94-010-6659-4Published: 28 September 2011

  • eBook ISBN: 978-94-009-0385-2Published: 06 December 2012

  • Series ISSN: 0928-8945

  • Edition Number: 1

  • Number of Pages: 296

  • Topics: Oncology, Pharmacology/Toxicology, Cancer Research

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