Skip to main content
SpringerLink
Log in
Book cover
  • Book
  • © 1991

Drugs Looking for Diseases

Innovative Drug Research and the Development of the Beta Blockers and the Calcium Antagonists

Authors:

  1. Rein Vos

    1. Department of Pharmacology and Pharmacotherapeutics, University Centre for Pharmacy, University of Groningen, Groningen, The Netherlands

    View author publications

    You can also search for this author in PubMed   Google Scholar

Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 120)

Sections

Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (9 chapters)

  1. Front Matter

    Pages i-xxix
    PDF

  3. The architecture of drug discovery

    • Rein Vos
    Pages 21-70

  10. The enigma of drug discovery

    • Rein Vos
    Pages 267-279

  11. Back Matter

    Pages 281-381
    PDF
Back to top

About this book

We all know how much time, effort and money it takes to develop a new drug. Hundreds of chemical compounds have to be synthesized and thousands of different activities in biology, physiology, pharmacology, clinical investigation, management and marketing have to be initiated and coordinated. Each new drug starts a voyage of discovery through an unmapped terrain which is shrouded in mist and beset by pitfalls, as Dr. Rein Vos puts it in his absorbing inside story of the development of the beta-adrenoceptor blocking agents and the calcium antagonists. Indeed we know, for example, how long it took before the theory of Ahlquist of the alpha and beta adrenergic receptors was widely accepted. Similarly, it suffices to memorize shortly the difficulty of expanding the new concept of calcium antagonism through the national German boundaries into the world. This shows how laborious and complex pharmaceutical progress is, and we all will benefit from a deeper understanding of the process of innovative drug research.
Back to top

Keywords

Back to top

Authors and Affiliations

  • Department of Pharmacology and Pharmacotherapeutics, University Centre for Pharmacy, University of Groningen, Groningen, The Netherlands

    Rein Vos

Back to top

Bibliographic Information

  • Book Title: Drugs Looking for Diseases

  • Book Subtitle: Innovative Drug Research and the Development of the Beta Blockers and the Calcium Antagonists

  • Authors: Rein Vos

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-94-011-3796-6

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1991

  • Hardcover ISBN: 978-0-7923-0968-0Published: 31 December 1990

  • Softcover ISBN: 978-94-010-5689-2Published: 31 October 2012

  • eBook ISBN: 978-94-011-3796-6Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: XXX, 381

  • Topics: Cardiology, Philosophy of Medicine

Back to top

Publish with us

Policies and ethics

Back to top
Access via your institution

Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Search

Navigation