Skip to main content
SpringerLink
Log in

Lipids in Health and Disease

  • Book
  • © 2008

Overview

Editors:
  1. Peter J. Quinn

    1. Biochemistry Department, King’s College London, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Xiaoyuan Wang

    1. State Key Laboratory of Food Science and Technology, Jiangnan University, China

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • The lipids represent targets for cell regulation
  • Their role in signaling processes increasingly recognized
  • Their role in cell-cell recognition and social behaviour of cells is identified
  • Potential therapeutic targets for gene transfection

Part of the book series: Subcellular Biochemistry (SCBI, volume 49)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (22 chapters)

  1. Front Matter

    Pages I-XXI
    Download chapter PDF

  2. Fatty Acids

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Transcriptional Regulation of Hepatic Fatty Acid Metabolism

      • Hervé Guillou, Pascal G.P. Martin, Thierry Pineau
      Pages 3-47

    3. Modulation of Protein Function by Isoketals and Levuglandins

      • Sean S. Davies
      Pages 49-70

    4. Signalling Pathways Controlling Fatty Acid Desaturation

      • María Cecilia Mansilla, Claudia E. Banchio, Diego de Mendoza
      Pages 71-99

    5. Fatty Acid Amide Hydrolase: A Gate-Keeper of the Endocannabinoid System

      • Filomena Fezza, Chiara De Simone, Daniele Amadio, Mauro Maccarrone
      Pages 101-132

    6. Modulation of Inflammatory Cytokines by Omega-3 Fatty Acids

      • Jing X. Kang, Karsten H. Weylandt
      Pages 133-143

    7. Eicosanoids in Tumor Progression and Metastasis

      • Sriram Krishnamoorthy, Kenneth V. Honn
      Pages 145-168

    8. Fatty Acid Synthase Activity in Tumor Cells

      • Joy L. Little, Steven J. Kridel
      Pages 169-194

  3. Phospholipids

    1. Front Matter

      Pages 195-195
      Download chapter PDF

    2. Lipids in the Assembly of Membrane Proteins and Organization of Protein Supercomplexes: Implications for Lipid-linked Disorders

      • Mikhail Bogdanov, Eugenia Mileykovskaya, William Dowhan
      Pages 197-239

    3. Altered Lipid Metabolism in Brain Injury and Disorders

      • Rao Muralikrishna Adibhatla, J. F. Hatcher
      Pages 241-268

    4. Lysophospholipid Activation of G Protein-Coupled Receptors

      • Tetsuji Mutoh, Jerold Chun
      Pages 269-297

    5. Phospholipid-Mediated Signaling and Heart Disease

      • Paramjit S. Tappia, Tushi Singal
      Pages 299-324

    6. The Role of Phospholipid Oxidation Products in Inflammatory and Autoimmune Diseases

      • Norbert Leitinger
      Pages 325-350

    7. Mediation of Apoptosis by Oxidized Phospholipids

      • Gilbert O. Fruhwirth, Albin Hermetter
      Pages 351-367

  4. Sphingolipids

    1. Front Matter

      Pages 369-369
      Download chapter PDF

    2. Regulation of lipid metabolism by sphingolipids

      • Tilla S. Worgall
      Pages 371-385

    3. Multiple Roles for Sphingolipids in Steroid Hormone Biosynthesis

      • Natasha C. Lucki, Marion B. Sewer
      Pages 387-412

    4. Roles of Bioactive Sphingolipids in Cancer Biology and Therapeutics

      • Sahar A. Saddoughi, Pengfei Song, Besim Ogretmen
      Pages 413-440
Back to top

Keywords

About this book

Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.

Editors and Affiliations

  • Biochemistry Department, King’s College London, UK

    Peter J. Quinn

  • State Key Laboratory of Food Science and Technology, Jiangnan University, China

    Xiaoyuan Wang

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation