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Malignant Hyperthermia

Proceedings of the 3rd International Symposium on Malignant Hyperthermia, 1994

  • Conference proceedings
  • © 1996

Overview

Editors:
  1. Michio Morio

    1. Chugoku Rosai General Hospital, Hiroshima University, Kure, Hiroshima, Japan

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  2. Hirosato Kikuchi

    1. The First Department of Anesthesiology, Toho University School of Medicine, Ohta-ku, Tokyo, 143, Japan

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  3. Osafumi Yuge

    1. Department of Anesthesiology and Critical Care Medicine, Hiroshima University School of Medicine, Hiroshima, 734, Japan

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Table of contents (29 papers)

  1. Front Matter

    Pages II-XV
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  2. History of Malignant Hyperthermia

    1. Front Matter

      Pages 1-1
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    2. History of Malignant Hyperthermia

      • Beverley A. Britt
      Pages 3-17

  3. Clinical Classification and Incidence of Fulminant and Abortive Malignant Hyperthermia

    1. Front Matter

      Pages 19-19
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    2. The Incidence of Malignant Hyperthermia in Denmark

      • Helle Ørding, Diana Bendixen
      Pages 21-24

    3. Malignant Hyperthermia in Austria 1984–1993

      • Dorrit Heilinger, Eva Donner, Andrea Sauberer, Werner Hackl, Walter Mauritz
      Pages 25-32

    4. Clinical Classification and Incidence of Fulminant and Abortive Malignant Hyperthermia Reactions in Italy

      • V. Tegazzin, A. Accorsi, I. Moroni, D. Di Martino, V. Brancadoro, V. Peduto
      Pages 33-37

    5. The Epidemiology of Malignant Hyperthermia Events in North America

      • Marilyn Green Larach, Linda J. Fuhrmann, Gregory C. Allen
      Pages 39-41

    6. Clinical Classification and Incidence of Malignant Hyperthermia in Australia

      • Michael A. Denborough
      Pages 43-47

    7. Clinical Classification and Incidence of Malignant Hyperthermia in Japan

      • Osafumi Yuge, Michio Morio, Hirosato Kikuchi, Keiko Mukaida, Yasuhiro Maehara, Masakazu Nakao et al.
      Pages 49-56

  4. Muscular Testing of Malignant Hyperthermia

    1. Front Matter

      Pages 57-57
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    2. Testing for Malignant Hyperthermia in North America and Australia

      • Henry Rosenberg
      Pages 59-62

    3. Muscular Testing of Malignant Hyperthermia in Europe

      • F. R. Ellis
      Pages 63-66

    4. Caffeine Contracture of the Skinned Muscle Fiber in Malignant Hyperthermia and Neuromuscular Diseases

      • Akio Takagi, Makoto Araki, Susumu Kojima, Masayoshi Ida, Tomoji Watanabe
      Pages 67-73

    5. Calcium-Induced Calcium Release Test

      • Makoto Endo
      Pages 75-75

  5. Genetic Study of Malignant Hyperthermia

    1. Front Matter

      Pages 77-77
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    2. Mutations in the Skeletal Muscle Ryanodine Receptor (RYR1) Gene are Linked to Malignant Hyperthermia and Central-Core Disease

      • David H. MacLennan
      Pages 79-86

    3. Chromosome 17 Candidate Gene Analysis in a Population Referred Because of Suspected Susceptibility to Malignant Hyperthermia

      • Gary M. Vita, Antonel Olckers, Anne E. Jedlicka, Terry Heiman-Patterson, Alfred L. George, Jeffery E. Fletcher et al.
      Pages 87-93

    4. Disease Expression and Gene Expression Can Be Quite Distinct: Modulation of Skeletal Muscle Sodium Channels by the Human Myotonin Dystrophy Protein Kinase (HMPK)

      • J. Paul Mounsey, Puting Xu, J. Edward John III, John Gilbert, Allen D. Roses, J. Randall Moorman
      Pages 95-101

  6. Biological Study of Malignant Hyperthermia

    1. Front Matter

      Pages 103-103
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Keywords

About this book

In susceptible individuals, malignant hyperthermia (MH) can be triggered by various anesthetics during surgery. First described in 1960, research since then has concentrated on reducing the very high mortality rate associated with MH. Although significant progress in treatment has been made with the introduction of dantrolene sodium in 1979, many questions remain unanswered. Following on the results of more than 30 years of investigative efforts, the Third International Symposium on MH was held in Hiroshima, Japan, in 1994, immediately before the Seventh International Workshop on MH. Specialists in the field discussed the most up-to-date findings from the point of view of clinical classification, history, and incidence based on the evidence of epidemiology, diagnostic muscle testing, genetics, and biochemistry. These proceedings of the symposium present important keys to understanding the mechanism of MH and related syndromes at the genetic level and include procedures for the monitoring and care of patients. This volume will be invaluable not only for surgeons and anesthesiologists but also for physiologists and researchers.

Editors and Affiliations

  • Chugoku Rosai General Hospital, Hiroshima University, Kure, Hiroshima, Japan

    Michio Morio

  • The First Department of Anesthesiology, Toho University School of Medicine, Ohta-ku, Tokyo, 143, Japan

    Hirosato Kikuchi

  • Department of Anesthesiology and Critical Care Medicine, Hiroshima University School of Medicine, Hiroshima, 734, Japan

    Osafumi Yuge

Bibliographic Information

  • Book Title: Malignant Hyperthermia

  • Book Subtitle: Proceedings of the 3rd International Symposium on Malignant Hyperthermia, 1994

  • Editors: Michio Morio, Hirosato Kikuchi, Osafumi Yuge

  • DOI: https://doi.org/10.1007/978-4-431-68346-9

  • Publisher: Springer Tokyo

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Tokyo 1996

  • Hardcover ISBN: 978-4-431-70171-2Published: 01 March 1996

  • Softcover ISBN: 978-4-431-68348-3Published: 20 April 2014

  • eBook ISBN: 978-4-431-68346-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XV, 256

  • Topics: Anesthesiology

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