Overview
- Editors:
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Masaaki Inaba
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Graduate School of Medicine, Osaka City University, Osaka, Japan
Reviews the latest findings on musculoskeletal diseases associated with diabetes
Maximizes reader insight into the mechanisms and clinical applications for bone and muscle diseases
Provides comprehensive knowledge for treating musculoskeletal diseases caused by diabetes
Includes supplementary material: sn.pub/extras
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Table of contents (19 chapters)
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Front Matter
Pages i-viii
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Bone Diseases
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- Masahiro Yamamoto, Toshitsugu Sugimoto
Pages 27-42
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- Ryo Okazaki, Daisuke Inoue
Pages 43-61
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- Yasuo Imanishi, Masaaki Inaba
Pages 81-98
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Muscle Diseases
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Front Matter
Pages 125-125
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- Katsuhito Mori, Tomoaki Morioka, Koka Motoyama, Masanori Emoto
Pages 171-183
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- Toshinari Takamura, Hirofumi Misu, Shuichi Kaneko
Pages 185-199
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- Tomoaki Morioka, Katsuhito Mori, Koka Motoyama, Masanori Emoto
Pages 201-213
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- Masanori Emoto, Tomoaki Morioka, Hisayo Yokoyama, Yuko Sawada-Yamazaki, Koka Motoyama, Katsuhito Mori et al.
Pages 215-235
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- Ken Sugimoto, Chung-Chi Wang, Hiromi Rakugi
Pages 237-252
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- Masayuki Hosoi, Yosuke Yakushiji, Shiro Tanaka
Pages 269-277
About this book
The aim of this book is to review the latest findings on musculoskeletal disease associated with diabetes. It has been increasingly recognized that maintaining skeletal health is an important factor in achieving longevity in healthy subjects. Diabetes has been established as a disease independently associated with sarcopenia and increased risk of bone fracture resulting from osteoporosis; therefore, it is reasonable to maintain that musculoskeletal health is important in preserving good health. As either bone or muscle is intimately involved in the regulation of metabolic status, keeping the musculoskeletal system healthy is important for improving abnormal glucose metabolism toward normal levels and is vital, as well, for maintaining normal activities of daily living. Muscle is a target of insulin for enhancing the entry of glucose; thus it is conceivable that sarcopenia and muscle containing fat streaks causes insulin resistance in diabetic patients. Furthermore, bone is an organ that regulates Ca and Pi levels in serum by releasing or resorbing Ca and Pi to and from bone tissue. It is now known that bone is a definitive endocrine organ for regulating glucose metabolism and Pi metabolism by secreting osteocalcin and FGF-23 from osteocytes/osteoblasts. Readers will learn of the recent findings in this area, and this book will benefit physicians who deal with diabetes, particularly orthopedists and bone specialists, as well as all physical therapists.
Reviews
“Japanese authors review both bone and muscular complications of diabetes, but include also diseases of the joints and their relationship to the metabolic control. Mainly for adult endocrinologists, diabetologists and rheumatologists.” (Pediatric Endocrinology Reviews, Vol. 13 (4), June, 2016)
Editors and Affiliations
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Graduate School of Medicine, Osaka City University, Osaka, Japan
Masaaki Inaba
About the editor
Masaaki Inaba MD Ph.D.
A professor of Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine.
