Editors:
Presents an international comparison of the pathogenesis and treatment of IgA nephropathy
Covers genetic variation, aberrant IgA1 production, and classification etiology, guidelines, and treatment goals
Forms an essential reference for the clinician who deals with this disease and also for the researcher who would like to learn about recent treatments in this field
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Table of contents (20 chapters)
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Front Matter
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Pathogenesis
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Front Matter
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Treatment
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Front Matter
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About this book
This book discusses the latest findings on the pathogenesis and treatment of IgA nephropathy. It particularly focuses on recently recognized initiation and progression factors and the varying treatment strategies in different regions, such as Asia, Europe, and the United States. More than 40 years have passed since Dr. Jean Berger first described primary IgA nephropathy (“Nephropathy with mesangial IgA-IgG deposits”) as a new disease entity.
Immunohistopathologically, IgA nephropathy is characterized by the granular deposition of IgA (IgA1) and C3 in the glomerular mesangial areas with mesangial cell proliferation and the expansion of mesangial matrices. It is clear that IgA nephropathy is one of the most common types of chronic glomerulonephritis in the world. This disease may lead to end-stage kidney disease, with its enormous economic impact on healthcare everywhere. Efforts by many investigators around the world have gradually clarified various aspects of the pathogenesis and treatment of IgA nephropathy. However, there are many controversial strategies for the treatment of patients with IgA nephropathy throughout the world, as there are several limitations for treatment in each country. This volume provides nephrologists everywhere with an overview and comparison of both global and regional findings in basic and clinical fields in IgA nephropathy. It covers genetic variation, aberrant IgA1 production, and classification etiology, guidelines, and treatment goals, with all chapters written by top international researchers.Reviews
Editors and Affiliations
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Tokyo 113-8421, Japan
Yasuhiko Tomino
About the editor
Editor: Dr. Yasuhiko Tomino
Division of Nephropathy, Department of Internal Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan
(Present address: Medical Corporation SHOWAKAI, Tokyo, Japan)
Bibliographic Information
Book Title: Pathogenesis and Treatment in IgA Nephropathy
Book Subtitle: An International Comparison
Editors: Yasuhiko Tomino
DOI: https://doi.org/10.1007/978-4-431-55588-9
Publisher: Springer Tokyo
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Japan 2016
Hardcover ISBN: 978-4-431-55587-2Published: 25 March 2016
Softcover ISBN: 978-4-431-56664-9Published: 25 April 2018
eBook ISBN: 978-4-431-55588-9Published: 10 March 2016
Edition Number: 1
Number of Pages: XI, 342
Number of Illustrations: 36 b/w illustrations, 10 illustrations in colour
Topics: Nephrology, Urology