Histamine and Anti-Histaminics

1. Front Matter

   Pages II-XXXV

   PDF

2. Chemistry, Isolation and Occurrence of Histamine

   1. Chemistry of Histamine and Analogs. Relationship between Structure and Pharmacological Activity

      • Reuben G. Jones

      Pages 1-43

   2. Die Isolierung von Histamin aus biologischem Material

      • Heinz Walter Raudonat

      Pages 44-56

   3. Determination of Histamine by Chemical Means

      • F. C. McIntire

      Pages 57-80

   4. Biological Determination of Histamine in Living Tissues and Body Fluids

      • I. Vugman, M. Rocha e Silva

      Pages 81-115

   5. The Occurrence of Histamine in Mast Cells

      • J. F. Riley, G. B. West

      Pages 116-135

   6. Histochimie des mastocytes

      • Lucien A. J. Lison

      Pages 136-147

3. Pharmacology of Histamine

   1. Absorption de l’histamine par l’appareil digestif

      • Jean-Louis Parrot, Georges Nicot

      Pages 148-161

   2. Captation de l’histamine par les protéines sériques

      • Jean-Louis Parrot, Claude Laborde-Burtin, Anatole Saindelle

      Pages 162-178

   3. Toxicity of Histamine: Lethal Doses

      • Plutarco Naranjo

      Pages 179-201

   4. Action de l’histamine sur les muscles lisses

      • Jean-Louis Parrot, Joseph Thouvenot

      Pages 202-224

   5. Action of Histamine on the Smooth Muscle

      • M. Rocha e Silva

      Pages 225-237

   6. Action of Histamine upon the Circulatory Apparatus

      • M. Rocha e Silva

      Pages 238-293

   7. Action of Histamine upon Salivary Glands

      • Nils Emmelin

      Pages 294-301

   8. Effect of Histamine on Gastric Secretion

      • A. C. Ivy, W. H. Bachrach

      Pages 302-317

   9. Relationship Between Histamine and the Autonomous Nervous System

      • U. S. v. Euler

      Pages 318-333

4. Release of Histamine

   1. Release of Histamine by Animal Venoms and Bacterial Toxins

      • W. T. Beraldo, W. Dias da Silva

      Pages 334-366

   2. Release of Histamine by Noxious Physical Agents, Organic Compounds and by Metals

      • Itamar Vugman

      Pages 367-385

   3. Histamine Release by Basic Compounds

      • Adolfo M. Rothschild

      Pages 386-430

   4. Release of Histamine in Anaphylaxis

      • M. Rocha e Silva

      Pages 431-480

It was an agreable, though strenuous task to edit a book with so many distin­ guished contributors, on a subject to which I have given half of my life. In 1959, when Prof. O. EICHLER invited me to edit a book on "Histamine and Anti­ histaminics", as a supplement to HEFFTER'S Handbuch, I thought the task could be done in three years. Now, five years are gone and only half is fulfilled. Though, so far as the "Histamine" part of the book is concerned, the initial plan has been followed very closely, we had to leave the Anti-histaminics for another volume of unpredictable dimensions. In 1924, eight pages inserted in a Chapter on M utterkorn, by ARTHUR R. CUSHING were considered enough, in vol. II, Part II, pg. 1319-1326, of the Handbuch. Now, 922 pages did not suffice to cover all the aspects of the subject. Especially in the last few years the subject has expanded in so many directions, that the antihistaminic part had to be excluded from the present volume. Possibly, another thousand pages will be necessary to cover what remains of the subject. In planning the book we made great use of the excellent and classical mono­ graph by W. FELDBERG and E. SCHILF on Histamin, published by Julius Springer, in 1930.

• Allergie
• Histamin
• Respiration
• absorption
• allergy
• asthma
• chemistry
• inflammation
• metabolism
• nervous system
• pharmacology
• planning
• toxicity

Policies and ethics