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Cell Culture in Pharmaceutical Research

  • Conference proceedings
  • © 1994

Overview

Editors:
  1. N. E. Fusenig

    1. Division of Differentiation and Carcinogenesis, Deutsches Krebsforschungszentrum, Heidelberg, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. H. Graf
    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 11)

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Table of contents (13 papers)

  1. Front Matter

    Pages I-XII
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  2. Cell Culture Models: Reliable Tools in Pharmacotoxicology?

    • N. E. Fusenig
    Pages 1-7

  3. Differentiation of Human Monocytes In Vitro: A Model of Macrophage Ontogeny

    • R. Andreesen, M. Kreutz
    Pages 9-27

  4. Embryonic Stem Cell Derived Cardiogenesis and Myogenesis

    • A. M. Wobus, J. Rohwedel, V. Maltsev, J. Hescheler
    Pages 29-57

  5. Embryonic Stem Cells as a Tool for Analyzing Mammalian Hematopoietic Development and Disease

    • E. F. Wagner
    Pages 59-67

  6. Tight Junctions and the Blood-Brain Barrier

    • L. L. Rubin, K. Herrenknecht, J. M. Staddon
    Pages 69-77

  7. Carcinogenesis Studies of Human Cells: Reliable In Vitro Models

    • N. E. Fusenig, P. Boukamp
    Pages 79-102

  8. The Use of Animal Tumor Models to Study the Role of the Tumor Microenvironment and Paracrine and Autocrine Growth Mechanisms in Metastasis to Specific Sites

    • G. L. Nicolson
    Pages 103-123

  9. Cellular Models for Angiogenesis Research

    • M. A. Rupnick, B. R. Zetter
    Pages 125-164

  10. Effects of Progesterone and Antiprogestins on Gonadotropin Secretion in the Model of Cultured Rat Pituitary Cells

    • O. Ortmann, S. S. Stojilkovic, K. J. Catt, K.-D. Schulz, G. Emons
    Pages 165-189

  11. Effect of Progesterone on Proteins Vectorially Secreted by Glandular Epithelial Cells of Guinea Pig Endometrium: Modulation by Homologous Stroma

    • A. Mahfoudi, M. Nicollier, G. L. Adessi
    Pages 191-213

  12. Steroids as Negative Regulators of Granulosa Cell Proliferation and Differentiation

    • J. J. Peluso
    Pages 215-237

  13. Applications of Expression Vectors Containing Bicistronic Transcription Units in Mammalian Cells

    • W. Dirks, C. Mielke, S. Karreman, B. Haase, M. Wirth, W. Lindenmaier et al.
    Pages 239-265

  14. Regulation of Progesterone Receptor Activity in Cell Culture Systems and Cell-Free Transcription

    • L. Vaßen, M. Klotzbücher, V. Ulber, G. U. Ryffel, L. Klein-Hitpass
    Pages 267-297

  15. Back Matter

    Pages 299-300
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Keywords

About this book

Cell biology has made an appreciable impact on the evaluation of physiological and pathophysiological processes leading to a more detailed understanding of the signaling mechanisms by which cells communicate in vivo and in vitro and modify adaptively. By using cell culture models in addition to animal experiments we are now able to better define the overall and the selective potential of drugs. This book is designed to give information on the advantages and limitations and on new aspects and the meaning of cell culture models in pharmaceutical research.

Editors and Affiliations

  • Division of Differentiation and Carcinogenesis, Deutsches Krebsforschungszentrum, Heidelberg, Germany

    N. E. Fusenig

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