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Hormones and Human Breast Cancer

An Account of 15 Years Study

  • Book
  • © 1970

Overview

Authors:
  1. John Hayward

    1. Breast Clinic, Guy’s Hospital, London S.E. 1, England

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Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 24)

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Table of contents (11 chapters)

  1. Front Matter

    Pages I-XV
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  2. Historical Developments

    1. Historical Developments

      • John Hayward
      Pages 1-9

  3. Hormones in Treatment and Prophylaxis

    1. The Ovaries

      • John Hayward
      Pages 10-31

    2. The Adrenals and the Pituitary

      • John Hayward
      Pages 32-51

    3. Tests of Prediction

      • John Hayward
      Pages 52-68

    4. Androgens and Oestrogens

      • John Hayward
      Pages 69-92

    5. Corticosteroids and Progestogens

      • John Hayward
      Pages 93-98

  4. The Hormonal Environment and Hormone Assays

    1. Antecedent and Racial Factors

      • John Hayward
      Pages 99-112

    2. Oestrogens

      • John Hayward
      Pages 113-120

    3. Androgens and Corticosteroids

      • John Hayward
      Pages 121-135

    4. Pituitary and Thyroid Hormones

      • John Hayward
      Pages 136-146

    5. The Present and the Future

      • John Hayward
      Pages 147-149

  5. Back Matter

    Pages 150-151
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Keywords

About this book

Seventeen years ago Mr. HAYWARD came to work in the Breast Clinic at Guy's Hospital. At that time the influence of hormones on the progress of breast cancer was appreciated; the prescription of androgens and oestrogens in the treatment of the advanced case was well established, and the operations of adrenalectomy and hypo­ physectomy had recently been introduced. Nevertheless, the prevailing view of the nature of breast cancer was that it was a local malignancy which had to be eradicated before it spread too widely and only if that had occurred would the aid of hormones be enlisted. How these hormones worked was unknown, indeed, today, as Mr. HAY­ WARD points out, their mode of action is still unknown. What has happened, however, within the last seventeen years has been a change of emphasis in our views regarding the essential nature of this disease. Instead of breast cancer being considered primarily as a local fault spreading centrifugally, it is realised with increasing con­ viction that it is a generalised disease with local manifestations and that one of the principal, if not the principal, aberration from normality lies in the endocrine environ­ ment. That this philosophy is demanding increasing acceptance is due in a significant measure to Mr. HAYWARD'S own investigations. In this work he has had the devoted assistance of BRIDGET WOLFF of the Breast Clinic at Guy's Hospital and the expert collaboration of Dr. R. D. BULBROOK of the Imperial Cancer Research Fund.

Authors and Affiliations

  • Breast Clinic, Guy’s Hospital, London S.E. 1, England

    John Hayward

Bibliographic Information

  • Book Title: Hormones and Human Breast Cancer

  • Book Subtitle: An Account of 15 Years Study

  • Authors: John Hayward

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-87015-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1970

  • Softcover ISBN: 978-3-642-87017-0Published: 15 August 2012

  • eBook ISBN: 978-3-642-87015-6Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XV, 151

  • Topics: Medicine/Public Health, general

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