Skip to main content
SpringerLink
Log in
Book cover

Microbial Resistance to Drugs

  • Book
  • © 1989

Overview

Editors:
  1. Lawrence E. Bryan

    1. Department of Microbiology and Infectious Diseases, Faculty of Medicine, University of Calgary, Health Sciences Centre, Calgary, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 91)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (18 chapters)

  1. Front Matter

    Pages I-XVII
    Download chapter PDF

  2. Role of the Outer Membrane of Gram-Negative Bacteria in Antimicrobial Resistance

    • H. Nikaido
    Pages 1-34

  3. Cytoplasmic Membrane Transport and Antimicrobial Resistance

    • L. E. Bryan
    Pages 35-57

  4. Susceptibility and Resistance of Plasmodium falciparum to Chloroquine

    • D. J. Krogstad, P. H. Schlesinger, I. Y. Gluzman
    Pages 59-75

  5. Resistance to β-Lactam Antibiotics Mediated by Alterations of Penicillin-Binding Proteins

    • B. G. Spratt
    Pages 77-100

  6. Plasmid-Determined Beta-Lactamases

    • A. A. Medeiros
    Pages 101-127

  7. The Chromosomal Beta-Lactamases

    • C. C. Sanders
    Pages 129-149

  8. Beta-Lactamases: Genetic Control

    • S. Chamberland
    Pages 151-167

  9. Resistance to Quinolones and Fluoroquinolones

    • L. J. V. Piddock
    Pages 169-192

  10. Ribosomal Changes Resulting in Antimicrobial Resistance

    • H. Hummel, A. Böck
    Pages 193-225

  11. Methylation of RNA and Resistance to Antibiotics

    • E. Cundliffe
    Pages 227-248

  12. Resistance to Trimethoprim

    • L. P. Elwell, M. E. Fling
    Pages 249-290

  13. Resistance to Sulfonamides

    • R. L. Then
    Pages 291-312

  14. Chloramphenicol Acetyltransferases

    • W. V. Shaw, A. G. W. Leslie
    Pages 313-324

  15. General Properties of Resistance Plasmids

    • D. E. Taylor
    Pages 325-357

  16. Clinical Laboratory Testing for Antimicrobial Resistance

    • F. D. Schoenknecht
    Pages 359-385

  17. The Molecular Epidemiology of Antimicrobial Resistance

    • D. M. Shlaes, C. A. Currie-McCumber
    Pages 387-410

  18. Microbial Persistence or Phenotypic Adaptation to Antimicrobial Agents: Cystic Fibrosis as an Illustrative Case

    • L. E. Bryan
    Pages 411-420

  19. Microbes Causing Problems of Antimicrobial Resistance

    • L. E. Bryan
    Pages 421-440

  20. Back Matter

    Pages 441-454
    Download chapter PDF
Back to top

Keywords

About this book

Most often when the subject of antimicrobial resistance is discussed, the organizational emphasis is on individual antimicrobial agents or groups of agents. Thus we tend to see discussion of resistance to f3-lactams, tetracyclines, amino­ glycosides etc. In this book many of the authors were asked to emphasize the mechanism of resistance in their discussion and from that to show how susceptibility to various agents was affected. In part this was done to help emphasize the enormous contribution that the study of antimicrobial resistance has made to our understanding of fundamental physiologic and genetic processes in bacteria. When one looks back over the study of antimicrobial resistance, it is clear that it has been the birthplace of many fundamental advances in molecular biology and of an appreciation of the role of many key functions in the life of a bacterium. In addition, and hopefully to an increasing extent in the future, such study has also contributed to advances in antimicrobial chemotherapy. Through­ out the book resistance mechanisms have been placed in perspective as to their significance as causes of resistance to key drugs or groups of drugs. Some are of much greater significance than others in terms of the prevalence or the degree of resistance produced. Whatever their numerical significance, however, each of the mechanisms, without question, throws light on fundamental cellular processes and the way in which they interact with antimicrobial agents.

Editors and Affiliations

  • Department of Microbiology and Infectious Diseases, Faculty of Medicine, University of Calgary, Health Sciences Centre, Calgary, Canada

    Lawrence E. Bryan

Bibliographic Information

  • Book Title: Microbial Resistance to Drugs

  • Editors: Lawrence E. Bryan

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-642-74095-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1989

  • Softcover ISBN: 978-3-642-74097-8Published: 10 December 2011

  • eBook ISBN: 978-3-642-74095-4Published: 06 December 2012

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XVII, 451

  • Topics: Pharmacology/Toxicology, Medical Microbiology, Pharmacy

Publish with us

Policies and ethics

Back to top

Search

Navigation