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Clinical Epidemiology and Biostatistics

A Primer for Clinical Investigators and Decision-Makers

  • Book
  • © 1988

Overview

Authors:
  1. Michael S. Kramer

    1. Faculty of Medicine, McGill University, Montreal, Canada

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Table of contents (19 chapters)

  1. Front Matter

    Pages I-XII
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  2. Epidemiologic Research Design

    1. Front Matter

      Pages 1-1
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    2. Introduction

      • Michael S. Kramer
      Pages 3-10

    3. Measurement

      • Michael S. Kramer
      Pages 11-24

    4. Rates

      • Michael S. Kramer
      Pages 25-36

    5. Epidemiologic Research Design: an Overview

      • Michael S. Kramer
      Pages 37-46

    6. Analytic Bias

      • Michael S. Kramer
      Pages 47-57

    7. Observational Cohort Studies

      • Michael S. Kramer
      Pages 58-77

    8. Clinical Trials

      • Michael S. Kramer
      Pages 78-92

    9. Case-Control Studies

      • Michael S. Kramer
      Pages 93-112

    10. Cross-Sectional Studies

      • Michael S. Kramer
      Pages 113-117

  3. Biostatistics

    1. Front Matter

      Pages 119-119
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    2. Introduction to Statistics

      • Michael S. Kramer
      Pages 121-123

    3. Descriptive Statistics and Data Display

      • Michael S. Kramer
      Pages 124-136

    4. Hypothesis Testing and P Values

      • Michael S. Kramer
      Pages 137-145

    5. Statistical Inference for Continuous Variables

      • Michael S. Kramer
      Pages 146-164

    6. Statistical Inference for Categorical Variables

      • Michael S. Kramer
      Pages 165-186

    7. Linear Correlation and Regression

      • Michael S. Kramer
      Pages 187-198

  4. Special Topics

    1. Front Matter

      Pages 199-199
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    2. Diagnostic Tests

      • Michael S. Kramer
      Pages 201-219
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Keywords

About this book

Here is a book for clinicians, clinical investigators, trainees, and graduates who wish to develop their proficiency in the planning, execution, and interpretation of clinical and epidemiological research. Emphasis is placed on the design and analysis of research studies involving human subjects where the primary interest concerns principles of analytic (cause-and- effect) inference. The topic is presented from the standpoint of the clinician and assumes no previous knowledge of epidemiology, research design or statistics. Extensive use is made of illustrative examples from a variety of clinical specialties and subspecialties. The book is divided into three parts. Part I deals with epidemiological research design and analytic inference, including such issues as measurement, rates, analytic bias, and the main forms of observational and experimental epidemiological studies. Part II presents the principles and applications of biostatistics, with emphasis on statistical inference. Part III comprises four chapters covering such topics as diagnostic tests, decision analysis, survival (life-table) analysis, and causality.

Authors and Affiliations

  • Faculty of Medicine, McGill University, Montreal, Canada

    Michael S. Kramer

Bibliographic Information

  • Book Title: Clinical Epidemiology and Biostatistics

  • Book Subtitle: A Primer for Clinical Investigators and Decision-Makers

  • Authors: Michael S. Kramer

  • DOI: https://doi.org/10.1007/978-3-642-61372-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1988

  • Softcover ISBN: 978-3-642-64814-4Published: 08 October 2011

  • eBook ISBN: 978-3-642-61372-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 286

  • Topics: Biostatistics, Epidemiology, Nursing, Rehabilitation, Statistics for Life Sciences, Medicine, Health Sciences

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