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Immunoreceptor Tyrosine-based Inhibition Motifs

  • Book
  • © 1999

Overview

Editors:
  1. Marc Daëron

    1. Laboratoire d’Immunologie Cellulaire et Clinique INSERM U.255, Institut Curie, Paris, France

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  2. Eric Vivier

    1. Centre d’Immunologie INSERM-CNRS de Marseille Luminy, Institut Universitaire de France, Marseille Cedex 9, France

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 244)

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Table of contents (15 chapters)

  1. Front Matter

    Pages I-VII
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  2. Biology of Immunoreceptor Tyrosine-based Inhibition Motif-Bearing Molecules

    • M. Daëron, E. Vivier
    Pages 1-12

  3. Negative Regulation of Hematopoietic Cell Activation and Proliferation by FcγRIIB

    • O. Malbec, W. H. Fridman, M. Daëron
    Pages 13-27

  4. The Role of the SRC Homology 2-Containing Inositol 5′-Phosphatase in FcɛR1-Induced Signaling

    • M. Huber, C. D. Helgason, J. E. Damen, M. P. Scheid, V. Duronio, V. Lam et al.
    Pages 29-41

  5. The Unexpected Complexity of FcγRIIB Signal Transduction

    • J. C. Cambier, D. Fong, I. Tamir
    Pages 43-55

  6. Regulation of B Cell Antigen Receptor Signaling by the Lyn/CD22/SHP1 Pathway

    • R. J. Cornall, C. C. Goodnow, J. G. Cyster
    Pages 57-68

  7. HLA-Specific and Non-HLA-Specific Human NK Receptors

    • A. Moretta, C. Bottino, R. Millo, R. Biassoni
    Pages 69-84

  8. Regulation of NK Cell Functions Through Interaction of the CD94/NKG2 Receptors with the Nonclassical Class I Molecule HLA-E

    • V. M. Braud, A. J. McMichael
    Pages 85-95

  9. Inhibitory Role of Murine Ly49 Lectin-like Receptors on Natural Killer Cells

    • M. Salcedo
    Pages 97-105

  10. gp49: An Ig-like Receptor with Inhibitory Properties on Mast Cells and Natural Killer Cells

    • N. Wagtmann
    Pages 107-113

  11. A Novel Family of Inhibitory Receptors for HLA Class I Molecules That Modulate Function of Lymphoid and Myeloid Cells

    • M. Colonna, F. Navarro, M. López-Botet
    Pages 115-122

  12. Interactions of LIRs, a Family of Immunoreceptors Expressed in Myeloid and Lymphoid Cells, with Viral and Cellular MHC Class I Antigens

    • L. Borges, N. Fanger, D. Cosman
    Pages 123-136

  13. Paired Immunoglobulin-like Receptors of Activating and Inhibitory Types

    • H. Kubagawa, M. D. Cooper, C. C. Chen, L. H. Ho, T. L. Alley, V. Hurez et al.
    Pages 137-149

  14. LAIR-1, a Widely Distributed Human ITIM-Bearing Receptor on Hematopoietic Cells

    • L. Meyaard
    Pages 151-157

  15. The Mast Cell Function-Associated Antigen, a New Member of the ITIM Family

    • R. Xu, I. Pecht
    Pages 159-168

  16. The Enigma of Activating Isoforms of ITIM-Bearing Molecules

    • A. Cambiaggi, M. Lucas, E. Vivier, F. Vély
    Pages 169-176

  17. Back Matter

    Pages 177-182
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Keywords

About this book

Novel molecular motifs named Immunoreceptor Tyrosine-based Inhibition Motifs (ITIMs) have recently been recognized in the intracytoplasmic domains of a still-increasing number of receptors which control cell activation and proliferation. Research on ITIM-bearing molecules has developed exponentially during the last three years, generating new concepts with important consequences in basic research and with exciting potential clinical applications. The present volume contains 15 reviews written by authors who all made significant contributions to the identification of ITIM-bearing molecules and the study of their biological properties. It constitutes the first synthesis ever published that is specifically devoted to this emerging topic.

Editors and Affiliations

  • Laboratoire d’Immunologie Cellulaire et Clinique INSERM U.255, Institut Curie, Paris, France

    Marc Daëron

  • Centre d’Immunologie INSERM-CNRS de Marseille Luminy, Institut Universitaire de France, Marseille Cedex 9, France

    Eric Vivier

Bibliographic Information

  • Book Title: Immunoreceptor Tyrosine-based Inhibition Motifs

  • Editors: Marc Daëron, Eric Vivier

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-58537-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1999

  • Hardcover ISBN: 978-3-540-65789-7Published: 25 June 1999

  • Softcover ISBN: 978-3-642-63634-9Published: 14 October 2012

  • eBook ISBN: 978-3-642-58537-1Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: VII, 183

  • Topics: Immunology, Cell Biology, Cancer Research

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