Overview
- Nominated by Peking University as an outstanding PhD thesis
- Comprehensively introduces the model study of Maoecrystal V
- Describes the first successful total synthesis of Maoecrystal V in detail
- Includes supplementary material: sn.pub/extras
Part of the book series: Springer Theses (Springer Theses)
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Table of contents (4 chapters)
Keywords
About this book
In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereo selective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures.
Authors and Affiliations
Bibliographic Information
Book Title: Total Synthesis of (±)-Maoecrystal V
Authors: Jianxian Gong
Series Title: Springer Theses
DOI: https://doi.org/10.1007/978-3-642-54304-3
Publisher: Springer Berlin, Heidelberg
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2014
Hardcover ISBN: 978-3-642-54303-6Published: 10 March 2014
Softcover ISBN: 978-3-662-51289-0Published: 03 September 2016
eBook ISBN: 978-3-642-54304-3Published: 08 July 2014
Series ISSN: 2190-5053
Series E-ISSN: 2190-5061
Edition Number: 1
Number of Pages: XII, 137
Number of Illustrations: 176 b/w illustrations, 1 illustrations in colour
Topics: Organic Chemistry, Medicinal Chemistry, Catalysis