Skip to main content
SpringerLink
Log in
Book cover

Specificity, Function, and Development of NK Cells

NK Cells: The Effector Arm of Innate Immunity

  • Book
  • © 1998

Overview

Editors:
  1. Klas Kärre

    1. Karolinska Institute, Microbiology and Tumor Biology Center, Stockholm, Sweden

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Marco Colonna

    1. Basel Institute for Immunology, Basel, Switzerland

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Presents recent advances on the function of natural killer cells

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 230)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (13 chapters)

  1. Front Matter

    Pages I-IX
    Download chapter PDF

  2. NK Receptors and Coreceptors

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Regulation of Mouse NK Cells by Structurally Divergent Inhibitory Receptors

      • L. L. Wang, W. M. Yokoyama
      Pages 3-13

    3. Stimulatory Receptors in NK and T Cells

      • A. Moretta, S. Sivori, M. Ponte, M. C. Mingari, L. Moretta
      Pages 15-23

    4. Killer Cell Inhibitory Receptor Expression by T Cells

      • A. D’Andrea, L. L. Lanier
      Pages 25-39

    5. The CD94/NKG2 C-Type Lectin Receptor Complex

      • M. López-Botet, M. Carretero, T. Bellón, J. J. Pérez-Villar, M. Llano, F. Navarro
      Pages 41-52

    6. Triggering of Natural Killer Cell Mediated Cytotoxicity by Costimulatory Molecules

      • B. J. Chambers, J. L. Wilson, M. Salcedo, K. Markovic, M. T. Bejarano, H. G. Ljunggren
      Pages 53-61

    7. Fc Receptors on Natural Killer Cells

      • B. Perussia
      Pages 63-88

    8. Adhesion in NK Cell Function

      • T. S. Helander, T. Timonen
      Pages 89-99

  3. Activation of NK Cells and Effector Functions

    1. Front Matter

      Pages 101-101
      Download chapter PDF

    2. Signal Transduction During NK Cell Activation: Balancing Opposing Forces

      • K. M. Brumbaugh, B. A. Binstadt, P. J. Leibson
      Pages 103-122

    3. Effector Pathways of Natural Killer Cells

      • M. F. Van den Broek, D. Kägi, H. Hengartner
      Pages 123-131

  4. Development of NK Cells

    1. Front Matter

      Pages 133-133
      Download chapter PDF

    2. Toward a Quantitative Analysis of the Repertoire of Class I MHC-Specific Inhibitory Receptors on Natural Killer Cells

      • R. E. Vance, D. H. Raulet
      Pages 135-160

    3. Ontogeny and Differentiation of Murine Natural Killer Cells and Their Receptors

      • P. V. Sivakumar, I. Puzanov, N. S. Williams, M. Bennett, V. Kumar
      Pages 161-190

  5. Role of NK Cells in Infections and Tumors

    1. Front Matter

      Pages 191-191
      Download chapter PDF

    2. Control of Infections by NK Cells

      • C. H. Tay, E. Szomolanyi-Tsuda, R. M. Welsh
      Pages 193-220

    3. Natural Killer Cells and Tumor Therapy

      • T. L. Whiteside, N. L. Vujanovic, R. B. Herberman
      Pages 221-244

  6. Back Matter

    Pages 245-250
    Download chapter PDF
Back to top

Keywords

About this book

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.

Editors and Affiliations

  • Karolinska Institute, Microbiology and Tumor Biology Center, Stockholm, Sweden

    Klas Kärre

  • Basel Institute for Immunology, Basel, Switzerland

    Marco Colonna

Bibliographic Information

  • Book Title: Specificity, Function, and Development of NK Cells

  • Book Subtitle: NK Cells: The Effector Arm of Innate Immunity

  • Editors: Klas Kärre, Marco Colonna

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-46859-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1998

  • Softcover ISBN: 978-3-642-46861-2Published: 08 March 2012

  • eBook ISBN: 978-3-642-46859-9Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: IX, 248

  • Topics: Immunology, Cancer Research, Hematology

Publish with us

Policies and ethics

Back to top

Search

Navigation