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  • © 2014

Molecular Mechanisms in Legionella Pathogenesis

Editors:

  • Written by leading authorities in the field
  • Provides an up-to-date and comprehensive? overview
  • Contributes to an in-depth-understanding of Legionnaires' disease
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 376)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-x
  2. From Amoeba to Macrophages: Exploring the Molecular Mechanisms of Legionella pneumophila Infection in Both Hosts

    • Pedro Escoll, Monica Rolando, Laura Gomez-Valero, Carmen Buchrieser
    Pages 1-34
  3. Facets of Small RNA-Mediated Regulation in Legionella pneumophila

    • Hana Trigui, Nilmini Mendis, Laam Li, Mariam Saad, Sebastien P. Faucher
    Pages 53-80
  4. Type II Secretion and Legionella Virulence

    • Nicholas P. Cianciotto
    Pages 81-102
  5. Modulation of Small GTPases by Legionella

    • Roger S. Goody, Aymelt Itzen
    Pages 117-133
  6. Phosphoinositide Lipids and the Legionella Pathogen Vacuole

    • Ina Haneburger, Hubert Hilbi
    Pages 155-173
  7. Legionella Phospholipases Implicated in Virulence

    • Katja Kuhle, Antje Flieger
    Pages 175-209
  8. Cytotoxic Glucosyltransferases of Legionella pneumophila

    • Yury Belyi, Thomas Jank, Klaus Aktories
    Pages 211-226
  9. Modulation of the Ubiquitination Machinery by Legionella

    • Andree Hubber, Tomoko Kubori, Hiroki Nagai
    Pages 227-247
  10. Host Signal Transduction and Protein Kinases Implicated in Legionella Infection

    • Andrew D. Hempstead, Ralph R. Isberg
    Pages 249-269
  11. Mouse Models of Legionnaires’ Disease

    • Andrew S. Brown, Ian R. van Driel, Elizabeth L. Hartland
    Pages 271-291
  12. Back Matter

    Pages 293-295

About this book

Legionnaires’ disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogen-host interactions, as well as host responses and immunity to L. pneumophila. Taken together, the contributions in this compilation provide a state-of-the-art overview of current insights into the molecular pathogenesis of the opportunistic and potentially fatal pathogen L. pneumophila.

Editors and Affiliations

  • Max von Pettenkofer Institute, Ludwig-Maximilians University München, Munich, Germany

    Hubert Hilbi

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access