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Micro-Segmented Flow

Applications in Chemistry and Biology

  • Book
  • © 2014

Overview

Editors:
  1. J. Michael Köhler

    1. Technical University Ilmenau Institute of Chemistry and Biotechnology, Ilmenau, Germany

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  2. Brian P. Cahill

    1. Institute for Bioprocessing and Analytical Measurement Techniques, Heilbad Heiligenstadt, Germany

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    You can also search for this editor in PubMed   Google Scholar

  • Introduces the most promising field of microfluidics and lab-on-a-chip technology
  • Explains the principle and the important application potential of micro-segmented flow
  • Introduces brand-new microfluidic approaches for generating high-quality nanomaterials
  • Presents droplet-based techniques for biological screenings
  • Includes supplementary material: sn.pub/extras

Part of the book series: Biological and Medical Physics, Biomedical Engineering (BIOMEDICAL)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xvii
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  2. Introduction

    • Brian P. Cahill
    Pages 1-3

  3. Generation, Manipulation and Characterization of Micro Fluid Segments

    1. Front Matter

      Pages 5-5
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    2. Droplet Microfluidics in Two-Dimensional Channels

      • Charles N. Baroud
      Pages 7-29

    3. Electrical Switching of Droplets and Fluid Segments

      • Matthias Budden, Steffen Schneider, J. Michael Köhler, Brian P. Cahill
      Pages 31-54

    4. Chip-Integrated Solutions for Manipulation and Sorting of Micro Droplets and Fluid Segments by Electrical Actuation

      • Lars Dittrich, Martin Hoffmann
      Pages 55-72

    5. Electrical Sensing in Segmented Flow Microfluidics

      • Brian P. Cahill, Joerg Schemberg, Thomas Nacke, Gunter Gastrock
      Pages 73-100

  4. Chemical Application in Micro Continuous-Flow Synthesis of Nanoparticles

    1. Front Matter

      Pages 101-101
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    2. Solid Particle Handling in Microreaction Technology: Practical Challenges and Application of Microfluid Segments for Particle-Based Processes

      • Frederik Scheiff, David William Agar
      Pages 103-148

    3. Micro Continuous-Flow Synthesis of Metal Nanoparticles Using Micro Fluid Segment Technology

      • Andrea Knauer, J. Michael Köhler
      Pages 149-200

  5. Biological Application: Cell-Free Biotechnology, Cell Cultivation and Screening Systems

    1. Front Matter

      Pages 201-201
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    2. Characterization of Combinatorial Effects of Toxic Substances by Cell Cultivation in Micro Segmented Flow

      • J. Cao, D. Kürsten, A. Funfak, S. Schneider, J. M. Köhler
      Pages 203-230

    3. Screening for Antibiotic Activity by Miniaturized Cultivation in Micro-Segmented Flow

      • Emerson Zang, Miguel Tovar, Karin Martin, Martin Roth
      Pages 231-265

  6. Back Matter

    Pages 267-272
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Keywords

About this book

The book is dedicated to the method and application potential of micro segmented flow. The recent state of development of this powerful technique is presented in 12 chapters by leading researchers from different countries. In the first section, the principles of generation and manipulation of micro-fluidic segments are explained. In the second section, the micro continuous-flow synthesis of different types of nanomaterials is shown as a typical example for the use of advantages of the technique in chemistry. In the third part, the particular importance of the technique in biotechnical applications is presented demonstrating the progress for miniaturized cell-free processes, for molecular biology and DNA-based diagnostics and sequencing as well as for the development of antibiotics and the evaluation of toxic effects in medicine and environment.

Editors and Affiliations

  • Technical University Ilmenau Institute of Chemistry and Biotechnology, Ilmenau, Germany

    J. Michael Köhler

  • Institute for Bioprocessing and Analytical Measurement Techniques, Heilbad Heiligenstadt, Germany

    Brian P. Cahill

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