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Vaccines against Allergies

  • Book
  • © 2011

Overview

  • We are celebrating this year the hundred years´ anniversary of allergen-specific immunotherapy.
  • In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing his attempts to achieve active immunity against “grass pollen toxin” by administering increasing doses of grass pollen extract before the grass pollen season to allergic patients.
  • Although it was unknown at that time that allergy represents an immunological hypersensitivity disease, the treatment was effective and many observations made by Noon remained valid until today.
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 352)

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Table of contents (10 chapters)

Keywords

About this book

We are celebrating this year the hundred years´ anniversary of allergen-specific immunotherapy. In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing his attempts to achieve active immunity against “grass pollen toxin” by administering increasing doses of grass pollen extract before the grass pollen season to allergic patients. Although it was unknown at that time that allergy represents an immunological hypersensitivity disease, the treatment was effective and many observations made by Noon remained valid until today. Today allergen-specific immunotherapy is well established as the only allergen-specific and disease-modifying treatment for IgE-mediated allergies and has long-lasting effects. In fact, more than 25% of the population suffer from IgE-mediated allergies which therefore represent a major health burden of our society, particularly because untreated allergy often progresses to severe disabling forms of disease, such as asthma and sometimes kills sensitized people through anaphylaxis.

Editors and Affiliations

  • Christian Doppler Laboratory for Allergy, Medical University of Vienna, Vienna, Austria

    Rudolf Valenta

  • Dynavax Technologies, Berkeley, USA

    Robert L. Coffman

Bibliographic Information

  • Book Title: Vaccines against Allergies

  • Editors: Rudolf Valenta, Robert L. Coffman

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-20054-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2011

  • Hardcover ISBN: 978-3-642-20053-3Published: 28 August 2011

  • Softcover ISBN: 978-3-642-27100-7Published: 25 November 2013

  • eBook ISBN: 978-3-642-20054-0Published: 26 August 2011

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XI, 182

  • Number of Illustrations: 20 b/w illustrations

  • Topics: Vaccine, Immunology

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