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The Chemokine System in Experimental and Clinical Hematology

  • Book
  • © 2010

Overview

Editors:
  1. Oystein Bruserud

    1. Dept. Medicine, Div. Infectious Diseases, Haukeland University Hospital, Bergen, Norway

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  • The aim of the issue is to describe and explain the importance of the chemokine system in hematology
  • The chemokine system is probably important for many aspects of normal as well as malignant hematopoiesis
  • A major focus is the development and treatment of hematologic malignancies, including the immunobiology of stem cell transplantation
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 341)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. The Chemokine System in Experimental and Clinical Hematology

    • Øystein Bruserud, Astrid Olsnes Kittang
    Pages 3-12

  3. Chemokine Decoy Receptors: Structure–Function and Biological Properties

    • Raffaella Bonecchi, Benedetta Savino, Elena M. Borroni, Alberto Mantovani, Massimo Locati
    Pages 15-36

  4. Role of Chemokines in the Biology of Natural Killer Cells

    • Azzam A. Maghazachi
    Pages 37-58

  5. Chemokines in Angiogenesis

    • Anna Dimberg
    Pages 59-80

  6. Genetic Polymorphisms in the Cytokine and Chemokine System: Their Possible Importance in Allogeneic Stem Cell Transplantation

    • Juergen Loeffler, Michael Ok, Oliver C. Morton, Markus Mezger, Hermann Einsele
    Pages 83-96

  7. The Chemokine System: A Possible Therapeutic Target in Acute Graft Versus Host Disease

    • Nicolai A. Kittan, Gerhard C. Hildebrandt
    Pages 97-120

  8. Homing in on Acute Graft vs. Host Disease: Tissue-Specific T Regulatory and Th17 Cells

    • Brian G. Engelhardt, James E. Crowe Jr
    Pages 121-146

  9. The Chemokine Network in Acute Myelogenous Leukemia: Molecular Mechanisms Involved in Leukemogenesis and Therapeutic Implications

    • Astrid Olsnes Kittang, Kimberley Hatfield, Kristoffer Sand, HÃ¥kon Reikvam, Øystein Bruserud
    Pages 149-172

  10. CXCR4 in Clinical Hematology

    • Gary Calandra, Gary Bridger, Simon Fricker
    Pages 173-191

  11. Immunobiology of Heparin-Induced Thrombocytopenia

    • Per Morten Sandset
    Pages 193-202

  12. Back Matter

    Pages 203-206
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Keywords

About this book

The aim of the issue is to describe and explain the importance of the chemokine system in hematology. The chemokine system is probably important for many aspects of normal as well as malignant hematopoiesis. A major focus is the development and treatment of hematologic malignancies, including the immunobiology of stem cell transplantation. The present reviews illustrate that chemokines can be involved in leukemogenesis. The chemokine system is also important both for the crosstalk between malignant cells and their neighbouring nonmalignant stromal cells (including endothelial cells) as well as for immunoregulation in patients treated with allogeneic stem cell transplantation. Thus, chemokines are important both for the pathogenesis and treatment of hematological diseases.

Editors and Affiliations

  • Dept. Medicine, Div. Infectious Diseases, Haukeland University Hospital, Bergen, Norway

    Oystein Bruserud

Bibliographic Information

  • Book Title: The Chemokine System in Experimental and Clinical Hematology

  • Editors: Oystein Bruserud

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-12639-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2010

  • Hardcover ISBN: 978-3-642-12638-3Published: 30 August 2010

  • Softcover ISBN: 978-3-642-26465-8Published: 13 October 2012

  • eBook ISBN: 978-3-642-12639-0Published: 30 September 2010

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XII, 208

  • Topics: Cancer Research, Hematology

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