Skip to main content
SpringerLink
Log in
Book cover

Methylxanthines

  • Book
  • © 2011

Overview

Authors:
  1. Bertil B. Fredholm

    1. Dept. Physiology & Pharmacology, Karolinska Institute, Stockholm, Sweden

    View author publications

    You can also search for this author in PubMed   Google Scholar

  • 21 contributions written by world experts in the field
  • Provides an up-to-date and authoritative account of the pharmacology of methylxanthines
  • Discusses the actions of the different xanthines and the mechanisms involved
  • Includes supplementary material: sn.pub/extras

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 200)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 349.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 449.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 449.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (21 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Notes on the History of Caffeine Use

    • Bertil B. Fredholm
    Pages 1-9

  3. Distribution, Biosynthesis and Catabolism of Methylxanthines in Plants

    • Hiroshi Ashihara, Misako Kato, Alan Crozier
    Pages 11-31

  4. Pharmacokinetics and Metabolism of Natural Methylxanthines in Animal and Man

    • Maurice J. Arnaud
    Pages 33-91

  5. Inhibition of Cyclic Nucleotide Phosphodiesterases by Methylxanthines and Related Compounds

    • Sharron H. Francis, Konjeti R. Sekhar, Hengming Ke, Jackie D. Corbin
    Pages 93-133

  6. Methylxanthines and Ryanodine Receptor Channels

    • Serge Guerreiro, Marc Marien, Patrick P. Michel
    Pages 135-150

  7. Xanthines as Adenosine Receptor Antagonists

    • Christa E. Müller, Kenneth A. Jacobson
    Pages 151-199

  8. Theobromine and the Pharmacology of Cocoa

    • Hendrik Jan Smit
    Pages 201-234

  9. Propentofylline: Glial Modulation, Neuroprotection, and Alleviation of Chronic Pain

    • Sarah Sweitzer, Joyce De Leo
    Pages 235-250

  10. Methylxanthines, Seizures, and Excitotoxicity

    • Detlev Boison
    Pages 251-266

  11. Impacts of Methylxanthines and Adenosine Receptors on Neurodegeneration: Human and Experimental Studies

    • Jiang-Fan Chen, Yijuang Chern
    Pages 267-310

  12. Methylxanthines and Pain

    • Jana Sawynok
    Pages 311-329

  13. Methylxanthines and Sleep

    • Tarja Porkka-Heiskanen
    Pages 331-348

  14. Methylxanthines and Reproduction

    • Alba Minelli, Ilaria Bellezza
    Pages 349-372

  15. Methylxanthines During Pregnancy and Early Postnatal Life

    • Ulrika Ã…dén
    Pages 373-389

  16. Methylxanthines and the Kidney

    • Hartmut Osswald, Jürgen Schnermann
    Pages 391-412

  17. The Cardiovascular Effects of Methylxanthines

    • Niels P. Riksen, Paul Smits, Gerard A. Rongen
    Pages 413-437

  18. Methylxanthines in Asthma

    • Stephen L. Tilley
    Pages 439-456

  19. Methylxanthines and Inflammatory Cells

    • György Haskó, Bruce Cronstein
    Pages 457-468

  20. Methylxanthines, Inflammation, and Cancer: Fundamental Mechanisms

    • Akio Ohta, Michail Sitkovsky
    Pages 469-481
Back to top

Keywords

About this book

In the present volume of the Handbook of Experimental Pharmacology well known experts describe the actions of different xanthines with a focus on caffeine and theophylline. A special chapter is devoted to theobromine, an active component of chocolate, the actions of which are less well characterized. This book also presents the pharmacology of one xanthine derivative, propentofylline, as an example of a xanthine that has gone through extensive development for a novel therapeutic area.

Authors and Affiliations

  • Dept. Physiology & Pharmacology, Karolinska Institute, Stockholm, Sweden

    Bertil B. Fredholm

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation