Heterocycles from Carbohydrate Precursors

1. Front Matter

   Pages I-XII

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2. Manipulation of Carbohydrate Carbon Atoms for the Synthesis of Heterocycles

   • E. S. H. El Ashry, Y. El Kilany, N. M. Nahas

   Pages 1-30

3. Synthesis of Heterocycles from Glycosylamines and Glycosyl Azides

   • José G. Fernández-Bolaños, Ó López

   Pages 31-66

4. Heterocycles from Carbohydrate Isothiocyanates

   • José G. Fernández-Bolaños, Óscar López

   Pages 67-100

5. β-Lactams from Carbohydrates

   • Bartłomiej Furman, Zbigniew Kałuża, Agnieszka Stencel, Barbara Grzeszczyk, Marek Chmielewski

   Pages 101-132

6. Azide–Alkyne 1,3-Dipolar Cycloadditions: a Valuable Tool in Carbohydrate Chemistry

   • Francisco Santoyo-González, Fernando Hernández-Mateo

   Pages 133-177

7. Synthesis of Glycoporphyrins

   • José A. S. Cavaleiro, João P. C. Tomé, Maria A. F. Faustino

   Pages 179-248

8. New Developments in the Synthesis of Anisomycin and Its Analogues

   • A. El Nemr, E. S. H. El Ashry

   Pages 249-285

9. 1,3-Dipolar Cycloadditions of Sugar-Derived Nitrones and their Utilization in Synthesis

   • L. Fišera

   Pages 287-323

10. Anhydro Sugars: Useful Tools for Chiral Syntheses of Heterocycles

    • Khalid Mohammed Khan, Shahnaz Perveen, Wolfgang Voelter

    Pages 325-346

11. Back Matter

    Pages 347-354

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This book is a volume in the series Topics in Heterocyclic Chemistry.Itc- ers the key methods used for designing synthetic approaches to heterocycles from carbohydrates and the value and scope of these methods. Carbohydrates are widely distributed in nature and constitute the largest part of renewable biomasses. Moreover, many carbohydrates and their derivatives are comm- cially available at relatively cheap prices. Consequently their utilization is highly encouraged and economically they are of great signi?cance. Moreover, carbohydrates are highly functionalized compounds that can be readily deri- tized and/or cyclized to provide heterocyclic compounds. This book provides a modern account and an up-to-date description of the advancement in the synthesis of diverse heterocycles from carbohydrates. Carbohydrates can be considered as a source of chiral centers in addition to the variable modi?cation thereof. Herein the elaboration of the carbohydrate molecules for providing different heterocycles is the main objective and team efforts from leaders of the topics has been gathered in this volume. This book is designed to be suitable for students and researchers. It is highly recommended as a reference book and for teaching the fascinating topics related to carbohydrates, heterocycles and organic synthesis. In addition to its importance in academia, it is also an excellent source for information about the variety of methods used in the synthesis of heterocycles important to industry.

• Cycloaddition
• chemistry
• medicinal chemistry
• organic chemistry
• pharmaceutical chemistry
• stereochemistry

From the reviews:

"The authors of the various chapters do a good job of describing the different methods used to synthesize these important molecules. Overall, the book reads well … . It is essential reading for individuals doing research in this area of chemistry and will be of particular interest to chemists working in the pharmaceutical industry and to those with an interest in medicinal chemistry." (Cecilia H. Marzabadi, Journal of the American Chemical Society, Vol. 130 (9), 2008)

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