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Cross-Coupling Reactions

A Practical Guide

  • Book
  • © 2002

Overview

Editors:
  1. Norio Miyaura

    1. Division of Molecular Chemistry Graduate School of Engineering, Hokkaido University, Sapporo, Japan

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  • This series presents critical reviews of the present position and future trends in modern chemical research
  • Short and concise reports on chemistry, each written by the world renowned experts
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  • More information as well as the electronic version of the whole content available at:
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Part of the book series: Topics in Current Chemistry (TOPCURRCHEM, volume 219)

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Table of contents (6 chapters)

  1. Front Matter

    Pages I-IX
    Download chapter PDF

  2. Introduction to Cross-Coupling Reactions

    • Kohei Tamao, Norio Miyaura
    Pages 1-9

  3. Organoboron Compounds

    • Norio Miyaura
    Pages 11-59

  4. Organosilicon Compounds

    • Tamejiro Hiyama, Eiji Shirakawa
    Pages 61-85

  5. Organotin Compounds

    • Keigo Fugami, Masanori Kosugi
    Pages 87-130

  6. Practical Palladium Catalysts for C-N and C-O Bond Formation

    • Alex R. Muci, Stephen L. Buchwald
    Pages 131-209

  7. Direct Arylation via Cleavage of Activated and Unactivated C-H Bonds

    • Masahiro Miura, Masakatsu Nomura
    Pages 211-241

  8. Back Matter

    Pages 243-248
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Keywords

About this book

In 1972, a very powerful catalytic cycle for carbon-carbon bond formation was 2 first discovered by the coupling reaction of Grignard reagents at the sp -carbon. Over the past 30 years, the protocol has been substantially improved and expanded to other coupling reactions of Li,B,N,O,Al,Si,P,S,Cu,Mn,Zn,In,Sn, and Hg compounds. These reactions provided an indispensable and simple methodology for preparative organic chemists. Due to the simplicity and rel- bility in the carbon-carbon, carbon-heteroatom, and carbon-metalloid bo- formations,as well as high efficiency of the catalytic process,the reactions have been widely employed by organic chemists in various fields. Application of the protocol ranges from various syntheses of complex natural products to the preparation of biologically relevant molecules including drugs, and of sup- molecules, and to functional materials. The reactions on solid surfaces allow robot synthesis and combinatorial synthesis. Now, many organic chemists do not hesitate to use transition metal complexes for the transformation of org- ic molecules. Indeed, innumerable organic syntheses have been realized by the catalyzed reactions of transition metal complexes that are not achievable by t- ditional synthetic methods. Among these, the metal-catalyzed cross-coupling reactions have undoubtedly contributed greatly to the development of such a new area of “metal-catalyzed organic syntheses”. An excellent monograph for the cross-coupling reactions and other met- catalyzed C-C bond-forming reactions recently appeared in Metal-catalyzed Cross-coupling Reactions (Wiley-VCH,1998).

Reviews

 

It is also suitable for teaching advanced courses in organic and organometallic chemistry. Clearly, it is one of the best books in this important field of synthetic organic chemistry.

Editors and Affiliations

  • Division of Molecular Chemistry Graduate School of Engineering, Hokkaido University, Sapporo, Japan

    Norio Miyaura

Bibliographic Information

  • Book Title: Cross-Coupling Reactions

  • Book Subtitle: A Practical Guide

  • Editors: Norio Miyaura

  • Series Title: Topics in Current Chemistry

  • DOI: https://doi.org/10.1007/3-540-45313-X

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2002

  • Hardcover ISBN: 978-3-540-42175-7Published: 11 January 2002

  • Softcover ISBN: 978-3-642-07576-6Published: 01 December 2010

  • eBook ISBN: 978-3-540-45313-0Published: 01 July 2003

  • Series ISSN: 0340-1022

  • Series E-ISSN: 1436-5049

  • Edition Number: 1

  • Number of Pages: X, 248

  • Topics: Organic Chemistry, Inorganic Chemistry, Physical Chemistry

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