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Immunobiology of Natural Killer Cell Receptors

  • Book
  • © 2006

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Editors:
  1. R.W. Compans

    1. Atlanta

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  2. M.D. Cooper

    1. Birmingham

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  3. T. Honjo

    1. Kyoto

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  4. H. Koprowski

    1. Philadelphia

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  5. F. Melchers

    1. Basel

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  6. M.B.A. Oldstone

    1. La Jolla

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  7. S. Olsnes

    1. Oslo

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  8. M. Potter

    1. Bethesda

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  9. P.K. Vogt

    1. La Jolla

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  10. H. Wagner

    1. Munich

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  11. Eric Vivier

    1. Laboratory of NK Cells and Innate Immunity, Centre d’Immunologie de Marseille-Luminy (CIML), CNRS-INSERM-Université de la Méditerranée, Campus de Luminy, Marseille Cedex 09, France

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  12. Marco Colonna

    1. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 298)

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Table of contents (13 chapters)

  1. Front Matter

    Pages I-VII
    Download chapter PDF

  2. Strategies of Natural Killer Cell Recognition and Signaling

    • C. A. Stewart, E. Vivier, M. Colonna
    Pages 1-21

  3. Signal Transduction in Natural Killer Cells

    • A.W. MacFarlane IV, K. S. Campbell
    Pages 23-57

  4. Transcriptional Regulation of NK Cell Receptors

    • S. K. Anderson
    Pages 59-75

  5. Extending Missing-Self? Functional Interactions Between Lectin-like Nkrp1 Receptors on NK Cells with Lectin-like Ligands

    • B. F. M. Plougastel, W. M. Yokoyama
    Pages 77-89

  6. The CD2 Family of Natural Killer Cell Receptors

    • M. E. McNerney, V. Kumar
    Pages 91-120

  7. Immunobiology of Human NKG2D and Its Ligands

    • S. González, V. Groh, T. Spies
    Pages 121-138

  8. NKG2 Receptor-Mediated Regulation of Effector CTL Functions in the Human Tissue Microenvironment

    • B. Jabri, B. Meresse
    Pages 139-156

  9. Dendritic Cell-NK Cell Cross-Talk: Regulation and Physiopathology

    • L. Zitvogel, M. Terme, C. Borg, G. Trinchieri
    Pages 157-174

  10. NK Cell Activating Receptors and Tumor Recognition in Humans

    • C. Bottino, L. Moretta, A. Moretta
    Pages 175-182

  11. NK Cell Recognition of Mouse Cytomegalovirus-Infected Cells

    • S. M. Vidal, L. L. Lanier
    Pages 183-206

  12. NK Cell Receptors Involved in the Response to Human Cytomegalovirus Infection

    • M. Gumá, A. Angulo, M. López-Botet
    Pages 207-223

  13. The Impact of Variation at the KIR Gene Cluster on Human Disease

    • M. Carrington, M. P. Martin
    Pages 225-257

  14. NK Cells in Autoimmune Disease

    • S. Johansson, H. Hall, L. Berg, P. Höglund
    Pages 259-277

  15. Back Matter

    Pages 279-283
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Keywords

About this book

Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation, all of which cause stress in affected cells. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor. Such responses are mediated through two major effector functions, the direct cytolysis of target cells and the production of cytokines and chemokines. The authors focus here on the nature of recognition events by NK cells and address how these events are integrated to trigger these distinct and graded effector functions.

Editors and Affiliations

  • Atlanta

    R.W. Compans

  • Birmingham

    M.D. Cooper

  • Kyoto

    T. Honjo

  • Philadelphia

    H. Koprowski

  • Basel

    F. Melchers

  • La Jolla

    M.B.A. Oldstone, P.K. Vogt

  • Oslo

    S. Olsnes

  • Bethesda

    M. Potter

  • Munich

    H. Wagner

  • Laboratory of NK Cells and Innate Immunity, Centre d’Immunologie de Marseille-Luminy (CIML), CNRS-INSERM-Université de la Méditerranée, Campus de Luminy, Marseille Cedex 09, France

    Eric Vivier

  • Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA

    Marco Colonna

Bibliographic Information

  • Book Title: Immunobiology of Natural Killer Cell Receptors

  • Editors: R.W. Compans, M.D. Cooper, T. Honjo, H. Koprowski, F. Melchers, M.B.A. Oldstone, S. Olsnes, M. Potter, P.K. Vogt, H. Wagner, Eric Vivier, … Marco Colonna

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/3-540-27743-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2006

  • Hardcover ISBN: 978-3-540-26083-7Published: 20 October 2005

  • Softcover ISBN: 978-3-642-06545-3Published: 12 February 2010

  • eBook ISBN: 978-3-540-27743-9Published: 20 December 2005

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: VIII, 284

  • Topics: Immunology

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