Overview
- Editors:
-
-
David W. Self
-
Southwestern Medical Center, University of Texas, Dallas, U.S.A.
-
Julie K. Staley Gottschalk
-
School of Medicine, Yale University, West Haven, U.S.A.
Access this book
Other ways to access
Table of contents (13 chapters)
-
Front Matter
Pages i-xiii
-
- Garret D. Stuber, F. Woodward Hopf, Kay M. Tye, Billy T. Chen, Antonello Bonci
Pages 3-27
-
- Ingo Willuhn, Matthew J. Wanat, Jeremy J. Clark, Paul E. M. Phillips
Pages 29-71
-
- Deanne M. Buffalari, Ronald E. See
Pages 73-99
-
- Heather C. Lasseter, Xiaohu Xie, Donna R. Ramirez, Rita A. Fuchs
Pages 101-117
-
- Manoranjan S. D’Souza, Athina Markou
Pages 119-178
-
- Louk J. M. J. Vanderschuren, R. Christopher Pierce
Pages 179-195
-
-
- Diana Martinez, Rajesh Narendran
Pages 219-245
-
-
- Daniel J. Müller, Olga Likhodi, Andreas Heinz
Pages 277-299
-
- Robert Hester, Dan I. Lubman, Murat Yücel
Pages 301-318
-
- Warren K. Bickel, Richard Yi, E. Terry Mueller, Bryan A. Jones, Darren R. Christensen
Pages 319-341
-
- Ellen Edens, Alfredo Massa, Ismene Petrakis
Pages 343-386
-
Back Matter
Pages 387-392
About this book
Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioration of neural de?cits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, part of the Springer series on Current Topics in Behavioral Neurosciences, contains scholarly reviews by noted experts on multiple topics from both basic and clinical neuroscience ?elds.
