Cancer in Organ Transplant Recipients

1. Front Matter

   Pages I-XII

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2. De Novo Cancer in Organ Transplant Patients

   1. Front Matter

      Pages 1-1

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   2. Animal Models of Cancer Caused by Immunosuppression

      • M. R. Berger

      Pages 3-17

   3. Malignancies in Man After Organ Transplantation

      • L. J. Kinlen

      Pages 18-26

   4. Malignant Lymphoproliferation of Viral Origin in Transplant Patients

      • J.-L. Touraine

      Pages 27-32

   5. Clonality of Post-transplant Lymphoproliferative Diseases

      • D. W. Hanto

      Pages 33-45

   6. Post-transplant Kidney Cancers and Skin Cancers (Including Kaposi’s Sarcoma)

      • I. Penn

      Pages 46-53

3. Back Matter

   Pages 54-55

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4. Treatment of Cancer by Organ Transplantation

   1. Front Matter

      Pages 57-57

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   2. Liver Transplantation for Malignant Disease

      • N. V. Jamieson, R. Williams, R. Calne

      Pages 59-67

   3. Bone Marrow Transplantation

      • B. Dörken

      Pages 68-77

   4. Transplantation of the Upper Gastrointestinal Organs in Malignant Diseases

      • G. Otto

      Pages 78-83

5. Back Matter

   Pages 84-85

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6. Possible Causes of Cancer in Transplant Patients

   1. Front Matter

      Pages 87-87

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   2. The Nordic Project on Renal Transplantation and Cancer

      • S. A. Birkeland

      Pages 89-105

   3. Human Papillomaviruses

      • E.-M. de Villiers

      Pages 106-112

   4. Immune Response Directed Against Epstein-Barr Virus Carrier B Lymphocytes

      • E. Klein

      Pages 113-126

   5. Carcinogenic Effects of Immunosuppressive Drugs in Man

      • D. Schmähl, B. Bunk

      Pages 127-131

   6. Influence of Blood Transfusions and Immunosuppressive Therapy on Malignancies in Renal Transplant Recipients

      • A. Abramczuk, C. O. Köhler, A. Engelmann, D. Back, G. Opelz

      Pages 132-138

   7. Possible Causes of Cancer in Transplant Patients

      • I. Penn

      Pages 139-152

In about 5% of all organ (kidney, liver) transplant recipients, malignancies occur as a late complication of the massive immunosuppression. The malignancies are mainly skin cancers, lymphomas and renal carcinomas. The present book discusses the possible mechanisms of this type of tumorigenesis and inquires into possibilities of prevention. In particular, the described malignancies might be of viral origin. The book informs about a completely new type of carcinogenesis. Apart from the scientific aspects, it is of great practical value.

• Bösartigkeit
• Immunsuppression
• Krebs
• Transplantation
• carcinoma
• tumorigenesis
• hepatology

• Institut für Toxikologie und Chemotherapie, Deutsches Krebsforschungszentrum, Heidelberg, Germany

  Dietrich Schmähl

• Medical Center, College of Medicine, Department of Surgery, Unviersity of Cincinnati, Cincinnati, USA

  Israel Penn

Policies and ethics