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Cerebral Blood Flow

Mechanisms of Ischemia, Diagnosis, and Therapy

  • Book
  • © 2002

Overview

Authors:
  1. Michael R. Pinsky

    1. Department of Anesthesiology and Critical Care Medicine, University of Pittsburgh, Pittsburgh, USA

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Part of the book series: Update in Intensive Care Medicine (UICMSOFT)

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xv
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  2. Physiology and Pathophysiology

    1. Front Matter

      Pages 1-1
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    2. History of Cerebral Blood Flow Assessment

      • Walter D. Obrist
      Pages 3-6

    3. Neural Regulation of the Cerebral Circulation

      • Costantino Iadecola, Kiyoshi Niwa
      Pages 7-16

    4. Role of Endothelium in Regulation of the Brain Microcirculation

      • Frank M. Faraci
      Pages 17-25

    5. Molecular Pathogenesis of Cerebral Aneurysms: Current Concepts and Future Directions

      • Amin B. Kassam, David G. Peters, Michael B. Horowitz
      Pages 26-41

  3. Ischemic Brain Injury

    1. Front Matter

      Pages 43-43
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    2. Triggering Events in Ischemic Brain Damage

      • Bo K. Siesjö, Tibor Kristián, Hiroyuki Uchino
      Pages 45-59

    3. Ischemic Mechanisms in Traumatic Brain Injury

      • Patrick M. Kochanek, Kristy S. Hendrich, Kimberly D. Statler, Robert S.B. Clark, Larry W. Jenkins, Donald S. Williams et al.
      Pages 60-71

    4. Coupling and Compartmentation of Cerebral Blood Flow and Metabolism

      • Albert Gjedde
      Pages 72-95

    5. The Genetic Control of Ischemic Neuronal Cell Death

      • Steven H. Graham, Robert W Hickey
      Pages 96-105

    6. Cerebral Resuscitation from Temporary Complete Global Brain Ischemia

      • Peter Safar
      Pages 106-136

    7. The Ischemic Penumbra: Pathophysiology and Therapeutic Implications

      • Konstantin-Alexander Hossmann
      Pages 137-146

  4. Assessment of Cerebral Blood Flow

    1. Front Matter

      Pages 147-147
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    2. The Assessment of Determinants of Cerebral Oxygenation and Microcirculation

      • F.A. Pennings, G.J. Bouma, Can Ince
      Pages 149-164

    3. Computed Tomography Angiography and Perfusion Imaging of Acute Stroke

      • George Hunter, Leena M. Hamberg, Michael H. Lev, Ramon Gilberto Gonzales
      Pages 165-178

    4. The Use of Xenon/CT Cerebral Blood Flow Studies in Acute Stroke

      • Howard Yonas
      Pages 179-190

    5. Advances in Imaging in Ischemic Stroke

      • M. Moonis, Majaz Moonis, Marc Fisher
      Pages 191-200

    6. Assessment of Cerebrovascular Pathophysiology

      • Viken Babikian, Joao Gomes, Jaroslaw Krejza
      Pages 201-216

    7. Cerebral Blood Flow Measurement with Positron Emission Tomography

      • William J. Powers
      Pages 217-225
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Keywords

About this book

Cerebral Blood Flow: Quantifying Consciousness Although the heart may be the source of energy needed to generate blood flow,and other organs absolutely essential for normal living,the brain is the reason we are alive. The collected book chapters are aimed at addressing this most fundamental organ and its blood flow. These papers reflect detailed descriptions of similar topics presented over a two-day period as part of the 5th International Symposium on Applied Physiology of the Peripheral Circulation held in Pittsburgh, Pennsylvania, in June 2000. The symposium and this volume were organized into four distinct groupings that follow in a logical fashion. The initial papers focus on the basic unique physiology and pathophysiology of the cerebral circulation, including a historical reviewof the means to measure cerebral blood flow and its implications of the past 30 years. Dr. Walter D. Obrist was one of the original investigators to use radiolabeled markers to assess cerebral blood flow. His equations and initial studies form an impressive introduction to where we are now. As with much of the body's special organs, the brain too has many circulatory features unique to itself.These include the unique blood-brain barrier function ofthe endothelium, local neural regulation control, and intracranial pressure effects. These special issues,plus genetic factors that may predispose individuals to developing cere­ bral aneurysm, make up the initial section of the monograph.

Authors and Affiliations

  • Department of Anesthesiology and Critical Care Medicine, University of Pittsburgh, Pittsburgh, USA

    Michael R. Pinsky

Bibliographic Information

  • Book Title: Cerebral Blood Flow

  • Book Subtitle: Mechanisms of Ischemia, Diagnosis, and Therapy

  • Authors: Michael R. Pinsky

  • Series Title: Update in Intensive Care Medicine

  • DOI: https://doi.org/10.1007/978-3-642-56036-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2002

  • Hardcover ISBN: 978-3-540-42037-8Due: 29 November 2001

  • Softcover ISBN: 978-3-540-42684-4Published: 22 March 2002

  • eBook ISBN: 978-3-642-56036-1Published: 06 December 2012

  • Series ISSN: 1610-4056

  • Edition Number: 1

  • Number of Pages: XV, 312

  • Number of Illustrations: 29 b/w illustrations, 11 illustrations in colour

  • Topics: Intensive / Critical Care Medicine, Anesthesiology, Emergency Medicine

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