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Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery

  • Conference proceedings
  • © 2007

Overview

Editors:
  1. Edward Abraham

    1. Health Sciences Center, Division Pulmonary & Critical Care Medicine, University of Colorado, Denver, USA

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  2. Mervyn Singer

    1. Bloomsbury Institute of Intensive Care, Division Medicine, University College Hospital, London, UK

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Update in Intensive Care Medicine (UICMSOFT)

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Table of contents (31 papers)

  1. Front Matter

    Pages I-XIV
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  2. Setting the Scene

    1. Setting the Scene

      • J. L. Vincent
      Pages 1-14

  3. The Inflammatory Response

    1. Front Matter

      Pages 15-15
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    2. Genetics and Severe Sepsis

      • J. Texereau, V. Lemiale, J. -P. Mira
      Pages 17-33

    3. Cell Signaling Pathways of the Innate Immune System During Acute Inflammation

      • S. M. Opal, P. A. Cristofaro
      Pages 35-53

    4. Early-Onset Pro-inflammatory Cytokines

      • C. Kaech, T. Calandra
      Pages 55-66

    5. The Significance of HMGB1, a Late-Acting Pro-inflammatory Cytokine

      • E. Abraham
      Pages 67-75

    6. Nitric Oxide

      • J. Carré, M. Singer, S. Moncada
      Pages 77-95

    7. Involvement of Reactive Oxygen and Nitrogen Species in the Pathogenesis of Acute Lung Injury

      • S. Matalon, I. C. Davis, J. D. Lang Jr
      Pages 97-111

    8. Heat Shock Proteins in Inflammation

      • Z. Bromberg, Y. G. Weiss, C. S. Deutschman
      Pages 113-121

    9. Fibrosis in the Acute Respiratory Distress Syndrome

      • D. C. J. Howell, R. C. Chambers, G. J. Laurent
      Pages 123-135

    10. Resolution of Inflammation

      • G. Bellingan
      Pages 137-157

  4. The Cellular Immune Respone

    1. Front Matter

      Pages 159-159
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    2. Compartmentalized Activation of Immune Cells During Sepsis and Organ Dysfunction

      • J. -M. Cavaillon, M. Adib-Conquy
      Pages 161-182

    3. The Neutrophil in the Pathogenesis of Multiple Organ Dysfunction Syndrome

      • Z. Malam, J. C. Marshall
      Pages 183-201

    4. The Role of the Macrophage

      • J. Pugin
      Pages 203-210

    5. The Role of the Endothelium

      • W. C. Aird
      Pages 211-227

    6. Differential Effects of Pro-Inflammatory Mediators on Alveolar Epithelial Barrier Function

      • M. A. Matthay, J. -W. Lee
      Pages 229-235

  5. Mechanisms and Pathways of Dysfunction

    1. Front Matter

      Pages 237-237
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    2. Macrocirculatory Disturbances

      • D. De Backer
      Pages 239-247
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Keywords

About this book

There have been tremendous advances in understanding the cellular mechanisms involved in sepsis and contributing to the development of multiple organ dysfunction and mortality in this setting. The chapters in this book provide up-to-date insights into important pathways that are initiated by sepsis.

Editors and Affiliations

  • Health Sciences Center, Division Pulmonary & Critical Care Medicine, University of Colorado, Denver, USA

    Edward Abraham

  • Bloomsbury Institute of Intensive Care, Division Medicine, University College Hospital, London, UK

    Mervyn Singer

Bibliographic Information

  • Book Title: Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery

  • Editors: Edward Abraham, Mervyn Singer

  • Series Title: Update in Intensive Care Medicine

  • DOI: https://doi.org/10.1007/3-540-30328-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2007

  • Hardcover ISBN: 978-3-540-30157-8Published: 25 September 2006

  • Softcover ISBN: 978-3-540-30158-5Published: 27 August 2007

  • eBook ISBN: 978-3-540-30328-2Published: 11 October 2006

  • Series ISSN: 1610-4056

  • Edition Number: 1

  • Number of Pages: XV, 453

  • Topics: Intensive / Critical Care Medicine, Emergency Medicine

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