Cannabis Use Disorders

1. Front Matter

   Pages i-xii

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2. Introduction to Cannabis Use Disorders

   • Ivan D. Montoya, Susan R. B. Weiss

   Pages 1-6

3. Epidemiology of Cannabis Use Disorder

   • Marsha Lopez, Carlos Blanco

   Pages 7-12

4. Genetic Aspects of Cannabis Use Disorder

   • Lisa Blecha, Geneviève Lafaye, Amine Benyamina

   Pages 13-20

5. The Endogenous Cannabinoid System: A Cadre of Potential Therapeutic Targets

   • Steven G. Kinsey, Aron H. Lichtman

   Pages 21-29

6. Cannabidiol and Cannabis Use Disorder

   • María S. García-Gutiérrez, Francisco Navarrete, Adrián Viudez-Martínez, Ani Gasparyan, Esther Caparrós, Jorge Manzanares

   Pages 31-42

7. The Molecular Basis of Cannabinoid Activity: Application to Therapeutics Design and Discovery for Cannabis Use Disorders

   • David R. Janero, V. Kiran Vemuri, Alexandros Makriyannis

   Pages 43-54

8. Translation of CUD Therapeutics from Drug Discovery to the Clinic

   • Aidan J. Hampson, Robert L. Walsh

   Pages 55-62

9. Animal Models of Cannabis Use Disorder

   • Zuzana Justinova

   Pages 63-74

10. Human Laboratory Models of Cannabis Use Disorder

    • Caroline A. Arout, Evan Herrmann, Margaret Haney

    Pages 75-84

11. Clinical Manifestations of Cannabis Use Disorder

    • Alan J. Budney, Jacob T. Borodovsky, Ashley A. Knapp

    Pages 85-91

12. Cannabis Withdrawal

    • Nicolas J. Schlienz, Ryan Vandrey

    Pages 93-102

13. Cannabis and Cannabinoid Intoxication and Toxicity

    • Ziva D. Cooper, Arthur Robin Williams

    Pages 103-111

14. Psychiatric Comorbidity of Cannabis Use Disorder

    • David A. Gorelick

    Pages 113-125

15. The Association Between Cannabinoids and Psychosis

    • Sai Krishna Tikka, Deepak Cyril D’Souza

    Pages 127-155

16. Medical Consequences of Cannabis Use

    • Jag H. Khalsa, Ruben Baler

    Pages 157-167

17. Synthetic Cannabinoid Use

    • Laurent Karila, Amine Benyamina

    Pages 169-176

18. Cannabis Use Disorder During the Perinatal Period

    • Martha L. Velez, Chloe J. Jordan, Lauren M. Jansson

    Pages 177-188

19. Cannabis Use Disorder as a Developmental Disorder

    • Rachel L. Tomko, Amber N. Williamson, Aimee L. McRae-Clark, Kevin M. Gray

    Pages 189-199

20. Cannabinoids to Treat Cannabis Use Disorders

    • Christina A. Brezing, Frances R. Levin

    Pages 201-205

This book is an unbiased scientific compendium documenting the state-of-the-art in the etiology, diagnosis and treatment of Cannabis Use Disorders (CUD). Unlike any other current medical text, this volume focuses on the scientific aspects of CUDs and provides a resource for researchers, physicians and other health care providers who treat patients suffering from the disorder or its consequences. It begins by establishing the landscape of the disorder, including its prevalence, association with disabilities and comorbidities, and frequency of patients seeking treatment. The text delves into the complexity of the disorder in today’s environment by including the discoveries on the nature and extent of the endocannabinoid system as well as potential breakthroughs in safe and effective pharmacological and nonpharmacological treatments. Experts in the field contribute discussions on the most cutting-edge diagnostic and biological topics, including genetics, medicalconsequences, and clinical manifestations. The text also covers the challenges and risks presented by external factors, including social repercussions, protective factors, psychiatric comorbidities, withdrawal, and treatment services.

Cannabis Use Disorders is a vital resource for researchers, psychiatrists, psychologists, addiction medicine specialists, toxicologists, hospital administrators, nurses, social workers, and all health care professionals working with patients who misuse cannabis.

• Etiology of Cannabis Use Disorder
• The endocannabinoid system
• Psychiatric Complexity
• Treatment services
• Diagnosis

• Division of Pharma & Med Cons Drug Abuse, NIDA, NIH, Department of Health & Human Services, Bethesda, USA

  Ivan D. Montoya

• Division of Extramural Research, National Institute on Drug Abuse Division of Extramural Research, Bethesda, USA

  Susan R. B. Weiss

Ivan D. Montoya, M.D., M.P.H.
Deputy Director, Division of Therapeutics and Medical Consequences
National Institute on Drug Abuse – NIH
6001 Executive Blvd.
Bethesda, MD 20892

 

Susan R.B. Weiss, Ph.D.
Director, Division of Extramural Research
National Institute on Drug Abuse
6001 Executive Boulevard
Room 5274
MSC 9581
Bethesda, MD 20892-9581

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