Overview
- Highlights recent advances in mitochondrial RNA metabolism
- Increases the understanding of mitochondrial gene function
- Spans from mitochondrial interaction with nucleus and cytosol to human disease
Part of the book series: Nucleic Acids and Molecular Biology (NUCLEIC, volume 34)
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Table of contents (9 chapters)
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Front Matter
Keywords
About this book
Editors and Affiliations
About the editors
Jorge Cruz-Reyes is a Professor in the Department of Biochemistry & Biophysics, and Department of Genetics, Texas A&M University (TAMU).
Since he joined the faculty at TAMU in 2001 he has carried out studies of the RNA editing apparatus and mechanism in trypanosome mitochondria. More recently he began working on the development of lead compounds against in T. brucei and T. cruzi and molecular genetics of the potential targets. His multi-disciplinary research involves collaborations with several labs at TAMU and in other Universities in the USA and abroad.
He obtained a Master's degree in Biomedical Research from the Institute of Biotechnology in UNAM, Mexico. He received a Ph.D. in MolecularParasitology from the London School of Hygiene and Tropical Medicine, University of London. His interest in RNA biology and a prestigious Pew Fellowship Award led him to The Johns Hopkins School of Medicine, where he joined the lab of Barbara Sollner-Webb to work on trypanosome RNA editing during his postdoctoral training. Currently, he teaches courses in Molecular Genetics and RNA Biology. He also regularly serves in scientific review groups at the NIH and the NSF.
Dr. Michael W. Gray, Dalhousie University Dept. Biochem. & Molecular Biol. and Centre for Comparative Genomics and Evolutionary Bioinformatics (CGEB), Halifax, Nova Scotia, Canada. Email: m.w.gray@dal.ca
Michael W. Gray is Professor Emeritus in the Department of Biochemistry and Molecular Biology, Dalhousie University (Halifax, Nova Scotia, Canada), which he joined in 1970, serving as head from 2004 to 2007. Since 1970, he has carried out research on the structure, function, and evolution of organelles (particularly mitochondria) and of eukaryotic RNA processing pathways (particularly RNA modification and RNA editing). A focus on protists (eukaryotic microbes) and use of a comparative genomics approach has underpinned his research.
Gray obtained his BSc (1964) and PhD (1968) in biochemistry from the University of Alberta, Edmonton, subsequently moving to Stanford University for postdoctoral training (1968–70). During his tenure as a faculty member at Dalhousie University, he was a Fellow in the Program in Evolutionary Biology of the Canadian Institute for Advanced Research (1987–2007) and held a Tier I Canada Research Chair in Genomics and Genome Evolution (2001–08). He was elected to Fellowship in the Royal Society of Canada (1996) and the American Academy of Microbiology (2014). Currently, he serves as a member of the Steering Committee of the Centre for Comparative Genomics and Evolutionary Bioinformatics (CGEB) at Dalhousie University.
Bibliographic Information
Book Title: RNA Metabolism in Mitochondria
Editors: Jorge Cruz-Reyes, Michael W. Gray
Series Title: Nucleic Acids and Molecular Biology
DOI: https://doi.org/10.1007/978-3-319-78190-7
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-78189-1Published: 22 June 2018
Softcover ISBN: 978-3-030-08637-4Published: 01 February 2019
eBook ISBN: 978-3-319-78190-7Published: 12 June 2018
Series ISSN: 0933-1891
Series E-ISSN: 1869-2486
Edition Number: 1
Number of Pages: IX, 249
Number of Illustrations: 2 b/w illustrations, 37 illustrations in colour
Topics: Nucleic Acid Chemistry, Gene Expression, Eukaryotic Microbiology