Optimizing Breast Cancer Management

1. Front Matter

   Pages i-v

   PDF

2. Strategies to Maintain Fertility in Young Breast Cancer Patients

   • Elizabeth S. Constance, Molly B. Moravek, Jacqueline S. Jeruss

   Pages 1-13

3. Adjuvant Endocrine Therapy

   • Rena Shah, Ruth M. O’Regan

   Pages 15-29

4. Breast Cancer Screening: The Debate that Never Ends

   • Sarah M. Friedewald

   Pages 31-38

5. Management of the Axilla in Early Breast Cancer

   • Monica G. Valero, Mehra Golshan

   Pages 39-52

6. Is DCIS Overrated?

   • Joshua Feinberg, Rachel Wetstone, Dana Greenstein, Patrick Borgen

   Pages 53-72

7. Readdressing the Role of Surgery of the Primary Tumor in de Novo Stage IV Breast Cancer

   • Seema Ahsan Khan, Elizabeth S. M. DesJardin

   Pages 73-88

8. Advancements and Personalization of Breast Cancer Treatment Strategies in Radiation Therapy

   • Meena S. Moran

   Pages 89-119

9. Multi-gene Panel Testing in Breast Cancer Management

   • Christos Fountzilas, Virginia G. Kaklamani

   Pages 121-140

10. Advances in Endocrine Therapy for Postmenopausal Metastatic Breast Cancer

    • Lisa E. Flaum, William J. Gradishar

    Pages 141-154

11. Immune Checkpoint Blockade for Breast Cancer

    • April Swoboda, Rita Nanda

    Pages 155-165

12. Sexual Function Post-Breast Cancer

    • Lauren Streicher, James A. Simon

    Pages 167-189

This book presents expert opinions on a variety of key topics related to the management of breast cancer, with a focus on the implications of recent advances and research findings for clinical practice. It also explores the controversy regarding mammography screening and reviews the contribution of new imaging modalities. Considerable attention is paid to developments in surgical procedures, including the potential for the safe and effective use of sentinel lymph node dissection alone—even in patients with positive nodes—and to the advantages and contraindications of new radiotherapy techniques. Genetic aspects are discussed in detail, including an assessment of the role of genetic testing and the potential impact of genetic signatures on breast cancer management. New systemic strategies, such as anti-HER2 therapy, endocrine agents, and agents to reverse endocrine resistance, are considered, and the optimal use of chemotherapy for early-stage and advanced-stage disease is addressed. Inclosing, the book shares important new insights into lifestyle risk factors, risk reduction strategies, and survivor issues, including sexual dysfunction and fertility maintenance.

• Anti - HER2 Therapy
• Bisphosphonates
• Endocrine Resistance
• Non-invasive Breast Cancer
• Sentinel Lymph Node Dissection
• Triple Negative Breast Cancer
• Radiaton Oncology

• Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, USA

  William J. Gradishar

Policies and ethics