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  • © 2018

Biomaterials in Clinical Practice

Advances in Clinical Research and Medical Devices

  • Reviews biomaterials applications from the perspectives of different fields, ranging from medical applications to engineering

  • Reviews already proven results and state-of-the-art research in material development and practical applications in specific fields

  • Provides insights into both the material development demands and aspects of practical clinical applications

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-xv
  2. Short History of Biomaterials Used in Hip Arthroplasty and Their Modern Evolution

    • Saverio Affatato, Katarina Colic, Igor Hut, D. Mirjanić, S. Pelemiš, Aleksandra Mitrovic
    Pages 1-21
  3. Material Classes

    1. Front Matter

      Pages 23-23
    2. Progress Beyond the State-of-the-Art in the Field of Metallic Materials for Bioimplant Applications

      • Eva Pellicer, Martina Lorenzetti, Jordina Fornell, Maria Dolors Baró, Sasa Novak, Jordi Sort
      Pages 25-46
    3. Polymeric Biomaterials in Clinical Practice

      • Željka Marjanović-Balaban, Dijana Jelić
      Pages 101-117
    4. Polymeric Biomaterials Based on Polylactide, Chitosan and Hydrogels in Medicine

      • Aleksandra Mitrovic, Jelena Muncan, Igor Hut, Svetlana Pelemis, Katarina Colic, Lidija Matija
      Pages 119-147
    5. Polyethylene Based Polymer for Joint Replacement

      • Saverio Affatato, Sami Abdel Jaber, Paola Taddei
      Pages 149-165
    6. Ceramics for Hip Joint Replacement

      • Saverio Affatato, Sami Abdel Jaber, Paola Taddei
      Pages 167-181
    7. Metallic Biomaterials

      • Goran Radenković, Dušan Petković
      Pages 183-224
    8. Biodegradable Metals as Biomaterials for Clinical Practice: Iron-Based Materials

      • Fatima Zivic, Nenad Grujovic, Eva Pellicer, Jordi Sort, Slobodan Mitrovic, Dragan Adamovic et al.
      Pages 225-280
    9. Porous Metals in Orthopedics

      • Karel Lietaert, Ruben Wauthle, Jan Schrooten
      Pages 281-301
    10. Properties and Behavior of Shape Memory Alloys in the Scope of Biomedical and Engineering Applications

      • Vladimir Dunić, Radovan Slavković, Elzbieta A. Pieczyska
      Pages 303-331
    11. Bioactive Biomaterials: Potential for Application in Bone Regenerative Medicine

      • Jelena Najdanović, Jelena Rajković, Stevo Najman
      Pages 333-360
    12. Bioactive Coatings

      • Kwang Leong Choy, Matthias Schnabelrauch, Ralf Wyrwa
      Pages 361-406
    13. Nanometals in Cancer Diagnosis and Therapy

      • Sonia Prado-López, Noelia González-Ballesteros, M. Carmen Rodríguez-Argüelles
      Pages 407-428
  4. Biomaterial Properties and Characterization

    1. Front Matter

      Pages 429-429
    2. Chemical Bulk Properties of Biomaterials

      • Matthias Schnabelrauch
      Pages 431-459
    3. Assessment of Metallic Alloys Biocompatibility

      • Carme Nogués, Andreu Blanquer, Lleonard Barrios, Elena Ibañez
      Pages 461-475
    4. Determining the Biological Properties of Biomaterials In Vivo

      • Perica J. Vasiljević, Jelena Živković, Marija Vukelić-Nikolić, Stevo Najman
      Pages 477-499

About this book

This book covers the properties of biomaterials that have found wide clinical applications, while also reviewing the state-of-the-art in the development towards future medical applications, starting with a brief introduction to the history of biomaterials used in hip arthroplasty. 


The book then reviews general types of biomaterials – polymers, ceramics, and metals, as well as different material structures such as porous materials and coatings and their applications – before exploring various current research trends, such as biodegradable and porous metals, shape memory alloys, bioactive biomaterials and coatings, and nanometals used in the diagnosis and therapy of cancer. 


In turn, the book discusses a range of methods and approaches used in connection with biomaterial properties and characterization – chemical properties, biocompatibility, in vivo behaviour characterisation, as well as genotoxicity and mutagenicity – and reviews various diagnostic techniques: histopathological analysis, imagining techniques, and methods for physicochemical and spectroscopic characterization. 
Properties of stent deployment procedures in cardiovascular surgeries, from aspects of prediction, development and deployment of stent geometries are presented on the basis of novel modelling approaches. 


The last part of the book presents the clinical applications of biomaterials, together with case studies in dentistry, knee and hip prosthesis. Reflecting the efforts of a multidisciplinary team of authors, gathering chemical engineers, medical doctors, physicists and engineers, it presents a rich blend of perspectives on the application of biomaterials in clinical practice. The book will provide clinicians with an essential review of currently available solutions in specific medical areas, also incorporating non-medical solutions and standpoints, thus offering them a
broader selection of materials and implantable solutions. 
This work is the result of joint efforts of various academic and research institutions participating in WIMB Tempus project, 543898-TEMPUS-1-2013-1-ES-TEMPUS-JPHES, "Development of Sustainable Interrelations between Education, Research and Innovation at WBC Universities in Nanotechnologies and Advanced Materials where Innovation Means Business", co-funded by the Tempus Programme of the European Union.


Editors and Affiliations

  • Faculty of Engineering, University of Kragujevac, Kragujevac, Serbia

    Fatima Zivic, Nenad Grujovic

  • Medical Technology Laboratory, Rizzoli Orthopaedic Institute, Bologna, Italy

    Saverio Affatato

  • Faculty of Mechanical Engineering, University of Niš, Niš, Serbia

    Miroslav Trajanovic

  • Biomaterials Department, INNOVENT e.V., Jena, Germany

    Matthias Schnabelrauch

  • Institute for Materials Discovery, University College London, London, United Kingdom

    Kwang Leong Choy

About the editors

Fatima Zivic is an Assistant Professor at the Faculty of Engineering, University of Kragujevac, Serbia, where she teaches courses on: Biomaterials, Surface Modification Technologies, Metrology and Quality Control. Her research explores novel biomaterial structures and material characterisation (mechanical and structural properties).  
Saverio Affatato is a Medical Physicist at the Rizzoli Orthopaedic Institute (IOR) (www.ior.it/tecno). In addition, he is the Head of the "Wear Characterization of Joint Prostheses Research Unit" of the IOR’s Medical Technology Laboratory.

rial, sans-s Miroslav Trajanovic is a Full Professor at the Faculty of Mechanical Engineering, University of Nis, Serbia. He has more than 35 years of experience in the application of ICT in mechanical engineering and medicine and more than 250 published papers to his credit. He has broad expertise in the modeling of biomaterials’ structural design (scaffold structures,
bone grafts). In addition, he is the Serbian coordinator of the European EURAXESS services network. 
Matthias Schnabelrauch received his PhD in Polymer Chemistry from Friedrich-Schiller-University, Jena. After postdoctoral positions at the University of Zurich, ETH Zurich, and the Hans-
Knöll-Institute, Jena, he currently heads the Biomaterials Department of INNOVENT e. V., Jena, Germany. His main research interests are in the synthesis, characterisation and application of degradable biomaterials. He is the author/co-author of more than 150 peer-reviewed scientific papers and 50 patent applications. 
Nenad Grujovic is a Full Professor and Head of the Center for Information Technologies (http://cit.fink.rs) at the Faculty of Engineering, University of Kragujevac, Serbia. His research focuses on custom-made medical implants, tissue engineering, 3D printing and FEM modeling. He has led two clinical projects on custom-made implants used i
ont> of Ti-reinforced PMMA artificial ribs (in 2017) made using 3D printing. 
Kwang Leong Choy is a Professor of Materials Discovery at University College London and Director of the UCL Institute for Materials Discovery (http://www.ucl.ac.uk/institute-for-materials-discovery). She has authored over 220 peer-reviewed publications, including 3 books, and holds 20 patents on nanomaterials, thin films and coatings for structural, functional and biomedical applications.
 


Bibliographic Information

  • Book Title: Biomaterials in Clinical Practice

  • Book Subtitle: Advances in Clinical Research and Medical Devices

  • Editors: Fatima Zivic, Saverio Affatato, Miroslav Trajanovic, Matthias Schnabelrauch, Nenad Grujovic, Kwang Leong Choy

  • DOI: https://doi.org/10.1007/978-3-319-68025-5

  • Publisher: Springer Cham

  • eBook Packages: Engineering, Engineering (R0)

  • Copyright Information: Springer International Publishing AG 2018

  • Hardcover ISBN: 978-3-319-68024-8Published: 02 November 2017

  • Softcover ISBN: 978-3-319-88533-9Published: 01 September 2018

  • eBook ISBN: 978-3-319-68025-5Published: 20 October 2017

  • Edition Number: 1

  • Number of Pages: XV, 830

  • Number of Illustrations: 103 b/w illustrations, 194 illustrations in colour

  • Topics: Biomedical Engineering and Bioengineering, Biomaterials, Biochemical Engineering, Rehabilitation Medicine

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access