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Chromogranins: from Cell Biology to Physiology and Biomedicine

  • Book
  • © 2017

Overview

Editors:
  1. Tommaso Angelone

    1. Department of Biology, Ecology and Earth Sciences, University of Calabria, Arcavacata di Rende, Italy

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  2. Maria Carmela Cerra

    1. Department of Biology, Ecology and Earth Sciences, University of Calabria, Arcavacata di Rende, Italy

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  3. Bruno Tota

    1. Department of Biology, Ecology and Earth Science, University of Calabria, Arcavacata di Rende, Italy

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  • Updates the state-of-the art information on chromogranins for researchers, PhD students and Post-docs
  • Provides an integrated analysis of chromogranins biological significance in health and disease
  • Highlights the prognostic and diagnostic potential of chromogranins

Part of the book series: UNIPA Springer Series (USS)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-ix
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  2. History and Perspectives

    • Karen B. Helle
    Pages 1-19

  3. Secretogranin II: Novel Insights into Expression and Function of the Precursor of the Neuropeptide Secretoneurin

    • Reiner Fischer-Colbrie, Markus Theurl, Rudolf Kirchmair
    Pages 21-38

  4. Chromogranins as Molecular Coordinators at the Crossroads between Hormone Aggregation and Secretory Granule Biogenesis

    • O. Carmon, F. Laguerre, L. Jeandel, Y. Anouar, M. Montero-Hadjadje
    Pages 39-48

  5. Involvement of Chromogranin A and Its Derived Peptides to Fight Infections

    • Marie-Hélène Metz-Boutigue, Francis Schneider
    Pages 49-68

  6. Conserved Nature of the Inositol 1,4,5-Trisphosphate Receptor and Chromogranin Coupling and Its Universal Importance in Ca2+ Signaling of Secretory Cells

    • Seung Hyun Yoo
    Pages 69-81

  7. Chromogranin A in Endothelial Homeostasis and Angiogenesis

    • Flavio Curnis, Fabrizio Marcucci, Elisabetta Ferrero, Angelo Corti
    Pages 83-98

  8. Full Lenght CgA: A Multifaceted Protein in Cardiovascular Health and Disease

    • Bruno Tota, Maria Carmela Cerra
    Pages 99-112

  9. Cardiac Physio-Pharmacological Aspects of Three Chromogranin A-Derived Peptides: Vasostatin, Catestatin, and Serpinin

    • Tommaso Angelone, Bruno Tota, Maria Carmela Cerra
    Pages 113-131

  10. Comparative Aspects of CgA-Derived Peptides in Cardiac Homeostasis

    • Alfonsina Gattuso, Sandra Imbrogno, Rosa Mazza
    Pages 133-148

  11. Molecular and Cellular Mechanisms of Action of CgA-Derived Peptides in Cardiomyocytes and Endothelial Cells

    • Giuseppe Alloatti, Maria Pia Gallo
    Pages 149-168

  12. Chromogranin A-Derived Peptides in Cardiac Pre- and Post-conditioning

    • Claudia Penna, Pasquale Pagliaro
    Pages 169-193

  13. Naturally Occurring Single Nucleotide Polymorphisms in Human Chromogranin A (CHGA) Gene: Association with Hypertension and Associated Diseases

    • Nitish R. Mahapatra, Sajalendu Ghosh, Manjula Mahata, Gautam K. Bandyopadhyay, Sushil K. Mahata
    Pages 195-211

  14. Serpinin Peptides: Tissue Distribution and Functions

    • Y. Peng Loh, Niamh Cawley, Alicja Woronowicz, Josef Troger
    Pages 213-228

  15. Action and Mechanisms of Action of the Chromogranin A Derived Peptide Pancreastatin

    • N. E. Evtikhova, A. Pérez-Pérez, C. Jiménez-Cortegana, A. Carmona-Fernández, T. Vilariño-García, V. Sánchez-Margalet
    Pages 229-247

  16. Chromogranins and the Quantum Release of Catecholamines

    • Leandro Castañeyra, Michelle Juan-Bandini, Natalia Domínguez, José David Machado, Ricardo Borges
    Pages 249-260

  17. Back Matter

    Pages 261-267
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Keywords

About this book

The volume is designed to provide an integrated overview of the results from the last fifteen years of research on Chromogranins in relation to cell biology, physiology and biomedicine. The different chapters highlight novel activities of these proteins, including their role in granule biogenesis, hormone co-storage, stimulus-processing-secretion coupling, autonomic sympathetic/parasympathetic balance, immune and cardiocirculatory function, and the response to stress. Biomedical aspects are also illustrated with focus on the prognostic and diagnostic significance of Chromogranin in the presence of tumors, cardiovascular diseases and inflammatory conditions.

The volume is of interest for laboratory and clinical scientists, PhD and Post-doc students that will be inspired to go deep inside the molecular, biochemical, physiological, pharmacological and clinical aspects of these fascinating multifaceted proteins.

Editors and Affiliations

  • Department of Biology, Ecology and Earth Sciences, University of Calabria, Arcavacata di Rende, Italy

    Tommaso Angelone, Maria Carmela Cerra

  • Department of Biology, Ecology and Earth Science, University of Calabria, Arcavacata di Rende, Italy

    Bruno Tota

Bibliographic Information

  • Book Title: Chromogranins: from Cell Biology to Physiology and Biomedicine

  • Editors: Tommaso Angelone, Maria Carmela Cerra, Bruno Tota

  • Series Title: UNIPA Springer Series

  • DOI: https://doi.org/10.1007/978-3-319-58338-9

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-58337-2Published: 23 November 2017

  • Softcover ISBN: 978-3-319-86381-8Published: 05 September 2018

  • eBook ISBN: 978-3-319-58338-9Published: 09 November 2017

  • Series ISSN: 2366-7516

  • Series E-ISSN: 2366-7524

  • Edition Number: 1

  • Number of Pages: IX, 267

  • Number of Illustrations: 12 b/w illustrations, 4 illustrations in colour

  • Topics: Human Physiology, Animal Physiology, Molecular Medicine

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