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  • © 2017

Asymmetric Cell Division in Development, Differentiation and Cancer

  • Reviews the process of asymmetric cell division extensively
  • Highlights similarities between single-cell and multi-cellular organisms in development
  • Broadens the understanding of tumor development after misregulation in stem cells

Part of the book series: Results and Problems in Cell Differentiation (RESULTS, volume 61)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-vi
  2. Modeling Asymmetric Cell Division in Caulobacter crescentus Using a Boolean Logic Approach

    • Ismael Sánchez-Osorio, Carlos A. Hernández-Martínez, Agustino Martínez-Antonio
    Pages 1-21
  3. Wnt Signaling Polarizes C. elegans Asymmetric Cell Divisions During Development

    • Arielle Koonyee Lam, Bryan T. Phillips
    Pages 83-114
  4. Size Matters: How C. elegans Asymmetric Divisions Regulate Apoptosis

    • Jerome Teuliere, Gian Garriga
    Pages 141-163
  5. Drosophila melanogaster Neuroblasts: A Model for Asymmetric Stem Cell Divisions

    • Emmanuel Gallaud, Tri Pham, Clemens Cabernard
    Pages 183-210
  6. Asymmetric Divisions in Oogenesis

    • Szczepan M. Bilinski, Jacek Z. Kubiak, Malgorzata Kloc
    Pages 211-228
  7. Asymmetries in Cell Division, Cell Size, and Furrowing in the Xenopus laevis Embryo

    • Jean-Pierre Tassan, Martin Wühr, Guillaume Hatte, Jacek Kubiak
    Pages 243-260
  8. Asymmetric and Unequal Cell Divisions in Ascidian Embryos

    • Takefumi Negishi, Hiroki Nishida
    Pages 261-284
  9. Asymmetries and Symmetries in the Mouse Oocyte and Zygote

    • Agathe Chaigne, Marie-Emilie Terret, Marie-Hélène Verlhac
    Pages 285-299

About this book

This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer.

To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological and pathological conditions. The book also illustrates the importance of this process for evolution and our need to understand the background mechanisms, offering a valuable guide not only for students in the field of developmental biology but also for experienced researchers from neighboring fields.



Editors and Affiliations

  • IGDR, UMR 6290, CNRS, Université de Rennes 1, Rennes, France

    Jean-Pierre Tassan

  • Inst of Genetics & Dev of Rennes IG, CNRS/Unive Rennes 1 UMR 6290, Rennes Cedex, France

    Jacek Z. Kubiak

Bibliographic Information

  • Book Title: Asymmetric Cell Division in Development, Differentiation and Cancer

  • Editors: Jean-Pierre Tassan, Jacek Z. Kubiak

  • Series Title: Results and Problems in Cell Differentiation

  • DOI: https://doi.org/10.1007/978-3-319-53150-2

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-53149-6Published: 25 April 2017

  • Softcover ISBN: 978-3-319-85077-1Published: 21 July 2018

  • eBook ISBN: 978-3-319-53150-2Published: 12 April 2017

  • Series ISSN: 0080-1844

  • Series E-ISSN: 1861-0412

  • Edition Number: 1

  • Number of Pages: VI, 421

  • Number of Illustrations: 15 b/w illustrations, 81 illustrations in colour

  • Topics: Cell Cycle Analysis, Embryology, Stem Cells, Cancer Research

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access