Overview
- Focuses on recent advances in the molecular biology of Photorhabdus bacteria
- Emphasises the application of this new research to agriculture and medicine
- Discusses open questions and the need for further research
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 402)
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Table of contents (10 chapters)
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Front Matter
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Insecticidal Toxins and Virulence Regulation
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Front Matter
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Secondary Metabolism and its Regulation
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Front Matter
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Insect Immunity
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Front Matter
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Photorhabdus Asymbiotica and Human Pathogenicity
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Front Matter
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Practical Guides
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Front Matter
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Keywords
About this book
This book provides an essential update on the startling array of novel insecticidal toxins and drugs produced by the fascinating bacterium Photorhabdus. The respective chapters describe everything from the detailed molecular biology of the ‘Toxin complexes’ or Tc’s to the complexity of insect immune response in relation to both the bacterium and its nematode vector. The volume covers both primary (toxin production and regulation) and secondary (natural product synthesis and regulation) metabolism and emphasises the potential use of toxins and drugs in both agriculture and medicine. It also discusses in detail two totally novel quorum sensing mechanisms and the likely role of LuxR solos in sensing the presence of different bacterial hosts. Lastly, the book explores the unique case of P. asymbiotica, which seems to have evolved the ability to infect both insects and humans. This synthesis proves that Photorhabdus truly does offer a ‘gold mine’ for the discovery ofnovel insecticidal proteins and novel natural products with potential uses in agriculture and medicine alike.
Editors and Affiliations
Bibliographic Information
Book Title: The Molecular Biology of Photorhabdus Bacteria
Editors: Richard H. ffrench-Constant
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-319-52715-4
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017
Hardcover ISBN: 978-3-319-52714-7Published: 07 June 2017
Softcover ISBN: 978-3-319-84968-3Published: 01 August 2018
eBook ISBN: 978-3-319-52715-4Published: 26 May 2017
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: X, 213
Topics: Pharmacology/Toxicology, Bacteriology, Medical Microbiology, Agriculture, Immunology