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A Modern Approach to Biofilm-Related Orthopaedic Implant Infections

Advances in Microbiology, Infectious Diseases and Public Health Volume 5

Editors:

  • Provides a comprehensive overview of Prostetic Joint Infection (PJI)
  • Highlights potential causes, diagnosis and therapy of PJIs
  • With a special focus on the involvment of biofilms in PJIs
  • Written for scientists working on arthroplasty and newcomers to the field alike

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 971)

Part of the book sub series: Advances in Microbiology, Infectious Diseases and Public Health (AMIDPH)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-vi
  2. The Concept of Biofilm-Related Implant Malfunction and “Low-Grade Infection”

    • Carlo Luca Romanò, Delia Romanò, Ilaria Morelli, Lorenzo Drago
    Pages 1-13
  3. Mechanisms of Bacterial Colonization of Implants and Host Response

    • Christof Wagner, G. Maria Hänsch
    Pages 15-27
  4. Animal Models of Implant-Related Low-Grade Infections. A Twenty-Year Review

    • Arianna Barbara Lovati, Marta Bottagisio, Elena de Vecchi, Enrico Gallazzi, Lorenzo Drago
    Pages 29-50
  5. Antibacterial Bioactive Glass, S53P4, for Chronic Bone Infections – A Multinational Study

    • Nina Lindfors, Jan Geurts, Lorenzo Drago, J. J. Arts, Vesa Juutilainen, Pekka Hyvönen et al.
    Pages 81-92
  6. Prosthetic Joint Infections and Cost Analysis?

    • F. S. Haddad, A. Ngu, J. J. Negus
    Pages 93-100
  7. Algorithm to Diagnose Delayed and Late PJI: Role of Joint Aspiration

    • Olivier Borens, Pablo S. Corona, Lars Frommelt, Stergios Lazarinis, Michael Richard Reed, Carlo Luca Romano
    Pages 101-111
  8. Erratum: Antibacterial Bioactive Glass, S53P4, for Chronic Bone Infections – A Multinational Study

    • Nina Lindfors, Jan Geurts, Lorenzo Drago, J. J. Arts, Vesa Juutilainen, Pekka Hyvönen et al.
    Pages 115-116
  9. Back Matter

    Pages 117-119

About this book

This book discusses Prosthetic Joint Infection (PJI), which remains one of the most common problems necessitating revision arthroplasty. It pursues a multidisciplinary approach, bringing together opinions from the leading experts in the field. The book identifies the potential causes of these infections, provides sound diagnostic criteria guidelines, and explains how these prosthetic infections are managed from orthopedic surgery, clinical and diagnostic perspectives. 

PJI can lead to multiple revision surgeries and significant patient morbidity. Periprosthetic infection rates remain around 1–2% after primary total hip and knee arthroplasty and account for approximately 7–12% of all revision cases.

Orthopedic hardware infections are much-feared and costly complications that can occur when these devices are implemented both in traumatic cases as well as in joint replacement surgery. Because these infections can lead to higher morbidity, it is important to understand their pathophysiology and the principles behind their diagnosis and initial treatment.

The pathogenesis of these kinds of infections is intimately connected to the biofilm-producing trait characteristic of many microorganisms, which can have a critical effect on the likely success of treatments.  

The book offers a unique guide for all scientists working in arthroplasty who are seeking an update on the field, and for newcomers alike.



Editors and Affiliations

  • Department of Biomedical Sciences Health, University of Milan, Milan, Italy

    Lorenzo Drago

Bibliographic Information

  • Book Title: A Modern Approach to Biofilm-Related Orthopaedic Implant Infections

  • Book Subtitle: Advances in Microbiology, Infectious Diseases and Public Health Volume 5

  • Editors: Lorenzo Drago

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-319-52274-6

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017

  • Hardcover ISBN: 978-3-319-52273-9Published: 29 May 2017

  • Softcover ISBN: 978-3-319-84864-8Published: 01 August 2018

  • eBook ISBN: 978-3-319-52274-6Published: 16 May 2017

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: VI, 119

  • Number of Illustrations: 20 illustrations in colour

  • Topics: Medical Microbiology, Bacteriology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access