Authors:
- Provides insights into the latest trends in nanotechnology applied to magnetic drug targeting
- Clarifies the advantages and disadvantages of using silica-coated magnetic nanoparticles for biomedical applications
- Offers an overview of the toxicological features of silica-coated magnetic nanoparticles
- Enhances understanding of the application of nanoparticles in the treatment of various diseases which constitute current biomedical challenges
Part of the book series: SpringerBriefs in Molecular Science (BRIEFSMOLECULAR)
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Table of contents (8 chapters)
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Front Matter
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Back Matter
About this book
This brief offers a comprehensive discussion of magnetic targeted drug delivery of silica-coated nanodevices. Focusing on the latest trend in pharmaceutical applications of these nanodevices, a multidisciplinary overview is displayed, from synthesis and design to pharmacokenetics, biodistribution and toxicology.
Keywords
- Silica-coated magnetic nanoparticles for targeted drug delivery
- Synthesis of magnetic silica nanoparticles
- Magnetic silica nanodevices
- Drug loading in magnetic silica nanoparticles
- In vitro and in vivo studies of magnetic silica nanoparticles
- Biodistribution of magnetic silica nanoparticles
- Toxicology of silica-coated magnetic nanoparticles
Authors and Affiliations
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INQUISUR – CONICET , Universidad Nacional del Sur , Bahía Blanca, Argentina
Mariela A. Agotegaray, Verónica L. Lassalle
About the authors
1. Prof. Dr. Verónica Lassalle graduated as Bachelor in Chemistry on 2000 at the National University of South (UNS, Argentina). She obtained her PhD degree in Chemistry from Pilot Plant of Chemical Engineering (PLAPIQUI, Argentina) on 2006 in the topic “Chemical modification of SBS copolymers”. Currently, she is Senior Researcher (CONICET) and full Professor at the Chemistry Institute of South (INQUISUR), Bahía Blanca, Argentina. She participates of one Cooperation Project with Biotechnological and Genetic Engineering Centre (CIGB) from La Habana, Cuba, in the topic “Development and Research on biodrugs with antitumoral activity. A study on the delivery systems and intracellular signalization” granted by MinCyT (Argentina) and CITMA (Cuba).
2. Prof. Dr. Mariela A. Agotegaray was born in October 1982 in Bahia Blanca, Argentina. She obtained a degree in Biochemistry at the National University of the South, Bahia Blanca and at the same University she defended her doctoral thesis entitled "Coordination Complexes of Copper (II) with Fenoprofen. Chemical, Therapeutics and Toxicology”. She has developed postdoctoral studies at INQUISUR (Institute of Chemistry South), National University of the South, on "Synthesis of magnetic nanoparticles with applications in transportation and controlled release of non-steroidal anti-inflammatory drugs". She currently is Scientific Researcher for CONICET (National Council of Scientific and Technical Research) at INQUISUR, working on "Design of nanoparticles with magnetic properties and their application in the treatment of inflammatory and cardiovascular diseases”.
Bibliographic Information
Book Title: Silica-coated Magnetic Nanoparticles
Book Subtitle: An Insight into Targeted Drug Delivery and Toxicology
Authors: Mariela A. Agotegaray, Verónica L. Lassalle
Series Title: SpringerBriefs in Molecular Science
DOI: https://doi.org/10.1007/978-3-319-50158-1
Publisher: Springer Cham
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: The Author(s) 2017
Softcover ISBN: 978-3-319-50157-4Published: 12 January 2017
eBook ISBN: 978-3-319-50158-1Published: 04 January 2017
Series ISSN: 2191-5407
Series E-ISSN: 2191-5415
Edition Number: 1
Number of Pages: VIII, 89
Number of Illustrations: 1 b/w illustrations, 25 illustrations in colour
Topics: Nanotechnology, Nanochemistry, Pharmacology/Toxicology