Skip to main content
SpringerLink
Log in

Developing Drug Products in an Aging Society

From Concept to Prescribing

  • Book
  • © 2016

Overview

Editors:
  1. Sven Stegemann

    1. Graz University of Technology, Graz, Austria

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Focuses on drug product development and prescribing for older patients from a multidisciplinary and global perspective
  • Provides practical guidelines for developing drugs for this population
  • Discusses regulatory pathways for medicines for older patients
  • Includes supplementary material: sn.pub/extras

Part of the book series: AAPS Advances in the Pharmaceutical Sciences Series (AAPS, volume 24)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 279.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (38 chapters)

  1. Front Matter

    Pages i-xviii
    Download chapter PDF

  3. The Patient(s)

    1. Front Matter

      Pages 59-59
      Download chapter PDF

    2. Old, Very Old and Frail

      • Jean-Pierre Baeyens
      Pages 61-66

    3. Age and the Process of Aging

      • Paul A. F. Jansen
      Pages 67-86

    4. Comprehensive Geriatric Assessment

      • Jacob Blumenthal, Steven R. Gambert
      Pages 87-101

    5. Patients’ Clinical Characteristics, Disease Experience, and Perception

      • Sven Stegemann
      Pages 103-113

  4. Clinical Development of Drug Products for Older Adults

    1. Front Matter

      Pages 115-115
      Download chapter PDF

    2. Ethical Considerations in Performing Clinical Trials in and for Older People

      • Florian von Raison and Laurence Hugonot-Diener on behalf of the Geriatric Medicine Working Party (GMWP), European Forum of Good Clinical Practice (EFGCP)
      Pages 117-128

    3. Patient Reported Outcomes in Clinical Trials and Practice with Older Patients

      • Sven Stegemann
      Pages 129-138

    4. Pharmacokinetic and Pharmacodynamic Considerations in Elderly Population

      • Jatinder Kaur Mukker, Ravi Shankar Prasad Singh, Hartmut Derendorf
      Pages 139-151

    5. The Expectation to Treatment Model: A Framework for Adherence and Effectiveness

      • Sven Stegemann
      Pages 153-170

    6. Pharmacoepidemiology and Pharmacovigilance for Safety and Efficacy in Older People

      • Sarah N. Hilmer, Danijela Gnjidic
      Pages 171-188

  5. Product Development for Older Adults

    1. Front Matter

      Pages 189-189
      Download chapter PDF

    2. Defining Patient Centric Drug Product Design and Its Impact on Improving Safety and Effectiveness

      • Sven Stegemann
      Pages 191-216

    3. Dosing Considerations in Older Adults

      • Gregory J. Hughes, Judith L. Beizer
      Pages 217-224

    4. Oral Drug Product Use in the Elderly Patient Population

      • Robert L. Ternik
      Pages 225-246
Back to top

Keywords

About this book

This book aims to address the major aspects of future drug product development and therapy for older adults, giving practical guidance for the rational product and clinical development and prescribing of drug products to this ever growing segment of the population. With authors coming from key “aging” markets such as Europe, the USA, China and Japan, the book will provide valuable information for students, scientists, regulators, practitioners, and other healthcare professionals from academia, industry and regulatory bodies.

Reviews

“This book reviews a wide range of topics related to drug development for an aging population … . The intended audience includes practitioners and/or researchers interested in sharing multidisciplinary knowledge, research, and practice expertise to fill existing knowledge gaps in order to improve drug product development for older, very old, multimorbid, and frail individuals.” (Susan K. Romann, Doody's Book Reviews, February, 2017)

Editors and Affiliations

  • Graz University of Technology, Graz, Austria

    Sven Stegemann

About the editor

Sven Stegemann is the endowed professor for Patient-Centric Drug Product Design and Manufacturing at the Graz University of Technology and Director of Pharmaceutical Business Development at Capsugel. He is scientist, professor and advocate for multidisciplinary research on patient-centric drug products and affordable medicines. Prof. Stegemann trains the next generation of pharmaceutical scientists. His professional experience spans all stages of drug development and manufacturing--from early development through commercial manufacturing.His passion and research led him to found the Geriatric Medicine Society e.V. in 2009, a multidisciplinary network that aims to facilitate the development of age-appropriate medicines that older patients can easily and safely take. He also serves in various organizations as chairman or committee member to progress pharmaceutical sciences.
He has established a focus group on patient-centric drug development through the American Association of Pharmaceutical Scientists (AAPS).
As This is integral to improving the quality of life of patients in the future.
He has spoken at innumerable conferences around the world on patient-centric drug delivery, pharmaceutical product development for special patient populations, multiparticulate technologies, adherence, geriatric drug delivery, quality by design and added value generics.

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation