Atomic Evidence

1. Front Matter

   Pages i-vii

   PDF

2. The Protein Data Bank

   • David S. Goodsell

   Pages 1-4

3. Seeing Is Believing: Methods of Structure Solution

   • David S. Goodsell

   Pages 5-10

4. Visualizing the Invisible World of Molecules

   • David S. Goodsell

   Pages 11-16

5. The Twists and Turns of DNA

   • David S. Goodsell

   Pages 17-24

6. The Central Dogma

   • David S. Goodsell

   Pages 25-31

7. The Secret of Life: The Genetic Code

   • David S. Goodsell

   Pages 33-39

8. Evolution in Action

   • David S. Goodsell

   Pages 41-49

9. How Evolution Shapes Proteins

   • David S. Goodsell

   Pages 51-58

10. The Universe of Protein Folds

    • David S. Goodsell

    Pages 59-65

11. Order and Chaos in Protein Structure

    • David S. Goodsell

    Pages 67-76

12. Molecular Electronics

    • David S. Goodsell

    Pages 77-82

13. Green Energy

    • David S. Goodsell

    Pages 83-88

14. Peak Performance

    • David S. Goodsell

    Pages 89-97

15. Cellular Signaling Networks

    • David S. Goodsell

    Pages 99-105

16. GPCRs Revealed

    • David S. Goodsell

    Pages 107-111

17. Signaling with Hormones

    • David S. Goodsell

    Pages 113-120

18. Single-Molecule Chemistry: Enzyme Action and the Transition State

    • David S. Goodsell

    Pages 121-127

19. Seven Wonders of the World of Enzymes

    • David S. Goodsell

    Pages 129-138

20. Building Bodies

    • David S. Goodsell

    Pages 139-148

This book will take an evidence-based approach to current knowledge about biomolecules and their place in our lives, inviting readers to explore how we know what we know, and how current gaps in knowledge may influence the way we approach the information. Biomolecular science is increasingly important in our everyday life, influencing the choices we make about our diet, our health, and our wellness. Often, however, information about biomolecular science is presented as a list of immutable facts, discouraging critical thought. The book will introduce the basic tools of structural biology, supply real-life examples, and encourage critical thought about aspects of biology that are still not fully understood.

• DNA
• biomolecular
• cellular
• molecular
• protein
• structural biology
• Systems Biology

“This book should be in the library of every individual teaching biochemistry, molecular biology, and genetics. Goodsell provides references to the protein database for all presented images. Instructors can mine the images for teaching material that will make the invisible world real for students. … Atomic Evidence supplies a welcome menagerie for molecular biologists. Summing Up: Recommended. Upper-division undergraduates through professionals.” (R. M. Denome, Choice, Vol. 54 (7), March, 2017)

• The Scrip Res Ins & RCSB Protein Data Bk, La Jolla, USA

  David S. Goodsell

David Goodsell is an Associate Professor of Molecular Biology at the Scripps Research Institute, where he currently divides his time between research and science outreach. His research centers on methods for predicting and analyzing biomolecular complexes, and application of these methods to drug discovery and drug design. His science outreach work builds on his work in molecular graphics and computation. He currently authors a monthly column at the RCSB Protein Data Bank that presents molecular structure and function for general audiences. He has also written three general-interest books including "The Machinery of Life" and "Our Molecular Nature". He has also collaborated with science museums, filmmakers and popular authors on the creation of educational and outreach materials.

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